7-bromoindolin-2-one
7-Bromooxindole
CAS: 320734-35-8
Molecular Formula: C8H6BrNO
7-bromoindolin-2-one - Names and Identifiers
| Name | 7-Bromooxindole |
| Synonyms | 7-BROMOOXINDOLE 7-Bromooxindole 7-Bromo-2-oxindole 7-bromoindolin-2-one 7-CHLOROINDOLIN-2-ONE 7-chloro-1H-indol-2-ol 7-Bromo-1,3-dihydro-2H-indol-2-one 7-bromo-2,3-dihydro-1H-indol-2-one 7-CHLORO-1,3-DIHYDRO-2H-INDOL-2-ONE |
| CAS | 320734-35-8 |
| EINECS | 691-376-0 |
| InChI | InChI=1/C8H6BrNO/c9-6-3-1-2-5-4-7(11)10-8(5)6/h1-3H,4H2,(H,10,11) |
7-bromoindolin-2-one - Physico-chemical Properties
| Molecular Formula | C8H6BrNO |
| Molar Mass | 212.04 |
| Density | 1.666±0.06 g/cm3(Predicted) |
| Melting Point | 194-200°C |
| Boling Point | 358.8±42.0 °C(Predicted) |
| Flash Point | 170.8°C |
| Vapor Presure | 2.48E-05mmHg at 25°C |
| pKa | 13.22±0.20(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.625 |
7-bromoindolin-2-one - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Hazard Note | Irritant |
7-bromoindolin-2-one - Introduction
7-bromoooxindole (7-bromoooxindole) is an organic compound with the chemical formula C8H6BrNO. It is a white crystalline solid with some solubility.
Properties: 7-Bromooxindole is an important intermediate that can be used to construct carbon-carbon bonds and carbon-nitrogen bonds in organic synthesis reactions. It has high chemical reactivity and can be further functionalized.
Purpose: 7-bromoooxindole is a widely used organic synthesis reagent, commonly used in the preparation of biologically active compounds, natural products and other complex organic molecules. It also has important applications in drug discovery and pesticide synthesis.
Preparation method: There are two main preparation methods for 7-bromoooxindole. One is the reaction of indolone with ammonium hydrogen chlorite to give 7-bromoooxindole by the method of cischlorination. Another method is the reaction of indolinone and bromine to produce 7-Bromooxindole by direct bromination.
Safety information: 7-bromoooxindole is an organic compound and has certain toxicity. It is necessary to pay attention to personal protective measures during use, such as wearing gloves and protective glasses. At the same time, avoid contact with skin, eyes and inhalation of its odor. During storage, it should be sealed and kept away from fire and flammable materials. Due to its toxicity, it is necessary to keep away from children and animals and avoid eating by mistake.
Properties: 7-Bromooxindole is an important intermediate that can be used to construct carbon-carbon bonds and carbon-nitrogen bonds in organic synthesis reactions. It has high chemical reactivity and can be further functionalized.
Purpose: 7-bromoooxindole is a widely used organic synthesis reagent, commonly used in the preparation of biologically active compounds, natural products and other complex organic molecules. It also has important applications in drug discovery and pesticide synthesis.
Preparation method: There are two main preparation methods for 7-bromoooxindole. One is the reaction of indolone with ammonium hydrogen chlorite to give 7-bromoooxindole by the method of cischlorination. Another method is the reaction of indolinone and bromine to produce 7-Bromooxindole by direct bromination.
Safety information: 7-bromoooxindole is an organic compound and has certain toxicity. It is necessary to pay attention to personal protective measures during use, such as wearing gloves and protective glasses. At the same time, avoid contact with skin, eyes and inhalation of its odor. During storage, it should be sealed and kept away from fire and flammable materials. Due to its toxicity, it is necessary to keep away from children and animals and avoid eating by mistake.
Last Update：2024-04-09 19:05:49
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View History
7-bromoindolin-2-one
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phosphocholine chloride calcium salt tetrahydrate
夸西泮
polytetrafluoroethylene artificial blood vessel
Pigment red 104 (C.I. 77605)
isocajucarinolide
Acid Violet 1
Z-L-GLUTAMINYL-L-GLYCINE
14575-74-7
The thymus method sheen