Molecular Formula | C30H48O2 |
Molar Mass | 440.7 |
Density | 1.02 |
Melting Point | >181oC (dec.) |
Boling Point | 528.5±49.0 °C(Predicted) |
Specific Rotation(α) | (CHCl3)+78 |
Solubility | Insoluble in water, soluble in petroleum ether, n-hexane, ethyl acetate. |
Appearance | White needle crystal |
Color | White to Off-White |
pKa | 4.73±0.10(Predicted) |
Storage Condition | Hygroscopic, -20°C Freezer, Under inert atmosphere |
MDL | MFCD09953817 |
Physical and Chemical Properties | White crystalline powder, soluble in methanol and chloroform, derived from Gentiana macrophylla. |
Safety Description | 24/25 - Avoid contact with skin and eyes. |
HS Code | 29163990 |
Biological activity | Roburic acid is a tetra-ring triterpenoid compound in Gentiana macrophylla. As a COX inhibitor, the IC50 values for COX-1 and COX-2 are 5 and 9 μM respectively. |
target | COX-1 5 μ m (IC 50 ) COX-2 9 μ m (IC 50 ) |
chemical properties | white crystalline powder, soluble in methanol and chloroform, derived from Gentiana macrophylla. |
use | oak sakuric acid has anti-cancer and anti-oxidation effects. used for content determination/identification/pharmacological experiment, etc. Pharmacological effects: Gentiana macrophylla is mainly related to cold and heat, cold and dampness, wind arthralgia, limb joint pain, water and urine. |