677-22-5
tert-butylmagnesium chloride
CAS: 677-22-5
Molecular Formula: C4H9ClMg
677-22-5 - Names and Identifiers
| Name | tert-butylmagnesium chloride |
| Synonyms | tert-butylmagnesium chloride tert-butylmagnesium(1+) chloride |
| CAS | 677-22-5 |
| EINECS | 211-638-6 |
| InChI | InChI=1/C4H9.ClH.Mg/c1-4(2)3;;/h1-3H3;1H;/q;;+1/p-1/rC4H9Mg.ClH/c1-4(2,3)5;/h1-3H3;1H/q+1;/p-1 |
| InChIKey | ZDRJSYVHDMFHSC-UHFFFAOYSA-M |
677-22-5 - Physico-chemical Properties
| Molecular Formula | C4H9ClMg |
| Molar Mass | 116.872 |
| Density | 0.931 g/mL at 25 °C |
| Melting Point | -108℃ (Tetrahydrofuran) |
| Flash Point | 34 °F |
| Water Solubility | Miscible with alcohol and water. |
| Appearance | Clear brown to dark brown Liquid |
| Storage Condition | 2-8°C |
| Stability | Air & Moisture Sensitive |
| Use | Tert-butyl magnesium chloride is a format reagent, which can be used as a synthetic intermediate in pharmaceutical and chemical industry. Tert-butyl magnesium chloride can be used as a pharmaceutical chemical synthesis intermediates, mainly used in laboratory research and development and chemical pharmaceutical research and development process. |
677-22-5 - Risk and Safety
| Risk Codes | R12 - Extremely Flammable R14/15 - R19 - May form explosive peroxides R22 - Harmful if swallowed R34 - Causes burns R66 - Repeated exposure may cause skin dryness or cracking R67 - Vapors may cause drowsiness and dizziness R15 - Contact with water liberates extremely flammable gases R11 - Highly Flammable R14 - Reacts violently with water R37 - Irritating to the respiratory system R17 - Spontaneously flammable in air R40 - Limited evidence of a carcinogenic effect |
| Safety Description | S9 - Keep container in a well-ventilated place. S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S29 - Do not empty into drains. S33 - Take precautionary measures against static discharges. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S43 - In case of fire use ... (there follows the type of fire-fighting equipment to be used.) S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 3399 4.3/PG 1 |
| WGK Germany | 1 |
| FLUKA BRAND F CODES | 1-3-10 |
| HS Code | 29319090 |
| Hazard Class | 4.3 |
| Packing Group | I |
677-22-5 - Upstream Downstream Industry
677-22-5 - Introduction
melting point -108 ℃ (Tetrahydrofuran)
Density 0.931g/mL at 25 c
Flash point 34 °F
Storage conditions 2-8°C
Morphological Liquid
Color Clear brown to dark brown
Water solubility Miscible with alcohol and water.
Sensitivity Air & Moisture Sensitive
BRN 3535403
InChIKey ZDRJSYVHDMFHSC-UHFFFAOYSA-M
Preparation
Preparation of tert-butyl magnesium chloride: Use sandpaper to remove the oxide film on the surface of the magnesium strip and cut it into fine chips. Weighted 3.6g(0.15 mol) of magnesium chips, added to a four-neck flask equipped with a nitrogen protection device, a stirrer, a reflux condenser and a constant pressure drip funnel (CaCl2 drying tube is installed on the top of the reflux condenser tube), introduced nitrogen into the reaction bottle for about 10 min, removed the air in the four-neck flask, then adjusted the nitrogen flow rate, and continuously introduced extremely small nitrogen into the reaction system. 35 mL of refined tetrahydrofuran is added to the four-neck flask, then 13.9g(0.15 mol) of tert-butyl chloride is weighed, about 3.5g of tert-butyl chloride is added to the four-neck flask first, and the remaining 10.4g of tert-butyl chloride is mixed with 150 mL of refined tetrahydrofuran and then added to a constant pressure separatory funnel. Add a small grain of iodine, slightly hot, a small amount of bubbles are generated, the color of iodine recedes, it is advisable to keep the reaction system slightly boiling after the reaction is initiated, after dropping, stir for 3~4 h, until the magnesium chips disappear completely, showing a gray solution.
safety information
Dangerous goods mark f, c, f
Hazard category code 12-14/15-19-22-34-66-67-15-11-14-37-17-40
Safety instructions 9-16-26-29-33-36/37/39-43-45
Dangerous goods transportation number UN 3399 4.3/PG 1
WGK Germany 1
F 1-3-10
HazardClass 4.3
PackingGroup I
Customs code 29319090
Last Update：2024-04-10 22:29:15
Supplier List
Featured ProductsSpot supply
Product Name: tert-Butylmagnesium Chloride Visit Supplier Webpage Request for quotationCAS: 677-22-5
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: tert-butylmagnesium chloride Request for quotation
CAS: 677-22-5
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CAS: 677-22-5
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: tert-butylmagnesium chloride Request for quotationCAS: 677-22-5
Tel: +86-13776910623
Email: r@reformchem.com
Mobile: +86-13776910623
QQ: 3785839865
Wechat: chemical6666
Multiple Specifications
Product Name: TERT-BUTYLMAGNESIUM CHLORIDE Request for quotationCAS: 677-22-5
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Spot supply
Product Name: tert-Butylmagnesium Chloride Request for quotationCAS: 677-22-5
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: tert-Butylmagnesium Chloride Visit Supplier Webpage Request for quotationCAS: 677-22-5
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Featured ProductsSpot supply
Product Name: tert-Butylmagnesium Chloride Visit Supplier Webpage Request for quotationCAS: 677-22-5
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: tert-butylmagnesium chloride Request for quotation
CAS: 677-22-5
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CAS: 677-22-5
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: tert-butylmagnesium chloride Request for quotationCAS: 677-22-5
Tel: +86-13776910623
Email: r@reformchem.com
Mobile: +86-13776910623
QQ: 3785839865
Wechat: chemical6666
Multiple Specifications
Product Name: TERT-BUTYLMAGNESIUM CHLORIDE Request for quotationCAS: 677-22-5
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589
Spot supply
Product Name: tert-Butylmagnesium Chloride Request for quotationCAS: 677-22-5
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: tert-Butylmagnesium Chloride Visit Supplier Webpage Request for quotationCAS: 677-22-5
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
View History
677-22-5
二氯丙烯
醋酸亚汞
56586-13-1
p-Methoxybenzyl acetate
60925-76-0
Propargyl-PEG1-N3
N-ACETYLISONIPECOTIC ACID
59609-49-3
二氢辛可宁
二氯丙烯
醋酸亚汞
56586-13-1
p-Methoxybenzyl acetate
60925-76-0
Propargyl-PEG1-N3
N-ACETYLISONIPECOTIC ACID
59609-49-3
二氢辛可宁
Raw Materials for 677-22-5
Downstream Products for 677-22-5
4-tert-Butylcyclohexanol
2-Propanesulfinic acid,2-methyl-
2,2-DIMETHYL-1-BUTANOL
N-tert-butylhydroxylamine
2-Propanesulfinic acid,2-methyl-
2,2-DIMETHYL-1-BUTANOL
N-tert-butylhydroxylamine