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66323-49-7

3'-Amino-2',3'-dideoxyguanosine

CAS: 66323-49-7

Molecular Formula: C10H14N6O3

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66323-49-7 - Names and Identifiers

Name 3'-Amino-2',3'-dideoxyguanosine
Synonyms 3'-NH2-ddG
3'-AMINO-2'-DEOXY-D- GUANOSINE
3'-AMINO-2',3'-DIDEOXYGUANOSINE
3'-Amino-2',3'-dideoxyguanosine
Guanosine,3'-aMino-2',3'-dideoxy-
3'-Amino-2',3'-dideoxy-D-guanosine
9-(3-Amino-2,3-dideoxy-β-D-ribofuranosyl)guanine
2-Amino-9-[(2R,4S,5S)-4-amino-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
2-amino-9-[(2R,4S,5S)-4-amino-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6 -one
2-Amino-9-((2R,4S,5S)-4-amino-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one
CAS 66323-49-7
InChI InChI=1/C10H14N6O3/c11-4-1-6(19-5(4)2-17)16-3-13-7-8(16)14-10(12)15-9(7)18/h3-6,17H,1-2,11H2,(H3,12,14,15,18)/t4-,5+,6+/m0/s1

66323-49-7 - Physico-chemical Properties

Molecular FormulaC10H14N6O3
Molar Mass266.26
Density2.08g/cm3
Boling Point662.4°C at 760 mmHg
Flash Point354.4°C
Water SolubilitySoluble in water (50 mg/ml).
Vapor Presure1.88E-18mmHg at 25°C
AppearancePowder
ColorOff-white to Yellow
Storage Conditionunder inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index1.935
MDLMFCD09750824

66323-49-7 - Introduction

3 '-Amino-2',3 '-dideoxyguanosine is a nucleoside analog with the formula C10H15N5O3. The following is a detailed description of its nature, use, preparation and safety information:

Nature:
- 3 '-Amino-2',3 '-dideoxyguanosine is a white to pale yellow crystalline solid.
-It is insoluble in water, but soluble in some organic solvents, such as methanol and dimethyl sulfoxide.
-It is stable to heat and light, but easily degraded under acidic conditions.

Use:
- 3 '-Amino-2',3 '-dideoxyguanosine is commonly used to study the structure and function of RNA.
-It can be used as a probe for interaction with RNA to study the interaction mechanism between RNA and proteins, drugs, etc.
-Because it is a dideoxynucleoside, it can also be used to study the synthesis and degradation of DNA or RNA.

Preparation Method:
- 3 '-Amino-2',3 '-dideoxyguanosine is usually prepared by chemical synthesis.
-The specific preparation method includes the amination reaction of 2 ',3'-dideoxyguanosine to introduce an amino group into the 3 'position of the nucleoside.

Safety Information:
- 3 '-Amino-2',3 '-dideoxyguanosine is generally considered to have low toxicity under conventional conditions.
-Follow the laboratory's safe practices during operation, including wearing appropriate personal protective equipment.
-Hazardous environments such as exposure to heat, fire and strong acids should be avoided.
Last Update:2024-04-09 21:04:16
66323-49-7
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View History
66323-49-7
硫酸双氢霉素
1462-05-1
TSU-68 (SU6668)
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