Molecular Formula | C4H6O3 |
Molar Mass | 124.07 |
Boling Point | 52 °C(Press: 5 Torr) |
Storage Condition | Room Temprature |
Physical and Chemical Properties | Bioactive acetate acid sodium salt is a non-esterified fatty acid metabolite that is involved in the development of diabetes in humans. Acetic acid sodium salt induces oxidative stress and inhibits the assembly of very low density lipoprotein in bovine hepatocytes. |
In vitro study | Acetoacetic acid (0.6, 2.4, 4.8 mM) increases malondialdehyde (MDA) content in high-dose group (GH) group, decreases mRNA expression of Mn SOD, Cu/Zn SOD, and glutathione peroxidase (GSH-Px) in all groups, lowers catalase (CAT) mRNA expression in medial-dose group (GM), and GH groups. In addition, Acetoacetic acid down-regulates the mRNA expression of apolipoprotein B100 (ApoB100), apolipoprotein E (ApoE), and low density lipoprotein receptor (LDLR). Thus, VLDL assembly is decreased andtriglyceride (TG) accumulation is increased in these bovine hepatocytes. |