6-Hydroxy-3-Fluorone
Sieber Linker
CAS: 3722-51-8
Molecular Formula: C13H8O3
6-Hydroxy-3-Fluorone - Names and Identifiers
| Name | Sieber Linker |
| Synonyms | HF Sieber Linker SIEBER LINKER 3-Hydroxyxanthone 3-HYDROXYXANTHONE 6-HYDROXY-3-FLUORONE 6-Hydroxy-3-Fluorone SALOR-INT L254835-1EA Salor-Int L254835-1Ea 3-HYDROXY-XANTHEN-9-ONE 3-Hydroxy-Xanthen-9-One 3-Hydroxy-9H-xanthen-9-one SIEBER LINKER,3-HYDROXY-XANTHEN-9-ONE 3-Hydroxy-9H-Xanthen-9-One,3-Hydroxy-Xanthen-9-One |
| CAS | 3722-51-8 |
| EINECS | 1312995-182-4 |
| InChI | InChI=1/C13H8O3/c14-8-5-6-10-12(7-8)16-11-4-2-1-3-9(11)13(10)15/h1-7,14H |
| InChIKey | XCJHDJAODLKGLG-UHFFFAOYSA-N |
6-Hydroxy-3-Fluorone - Physico-chemical Properties
| Molecular Formula | C13H8O3 |
| Molar Mass | 212.2 |
| Density | 1.395±0.06 g/cm3(Predicted) |
| Melting Point | 243 °C |
| Boling Point | 403.9±24.0 °C(Predicted) |
| Flash Point | 162.9°C |
| Vapor Presure | 4.22E-07mmHg at 25°C |
| Appearance | Solid |
| Color | White to Orange to Green |
| pKa | 7.52±0.20(Predicted) |
| Storage Condition | Store at 0°C |
| Refractive Index | 1.679 |
| MDL | MFCD00604748 |
6-Hydroxy-3-Fluorone - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| HS Code | 29329900 |
6-Hydroxy-3-Fluorone - Introduction
Sieber Linker, also known as Sieber Linker, is a linker commonly used in organic synthesis. It has the following properties:
1. Structural stability: Sieber Linker has a stable chemical structure and can remain stable under conventional experimental conditions.
2. Good reproducibility: The use of Sieber Linker can achieve a high degree of reproducibility, which is conducive to the reliability of the experimental results.
3. Easy synthesis: The method of preparing Sieber Linker is relatively simple, and the common synthesis tail can be used for the synthesis of different compounds.
Sieber Linker is mainly used for connection reactions in organic synthesis. It can link two molecules or compounds in the nucleophilic group and electron affinity group together to form a new chemical bond. This linkage reaction is widely used in pharmaceutical research, ligand synthesis and polymer synthesis.
There are many methods for preparing Sieber Linker. Common methods include nucleophilic substitution, condensation reaction and electrophilic substitution. The specific preparation method can be selected according to the desired ligation reaction and the structure of the target compound.
When using Sieber Linker, you need to pay attention to some safety matters. It may be toxic to a certain extent, so proper precautions such as gloves, goggles and outside laboratory operations are required during operation. In addition, direct contact with the skin and inhalation of its gas or dust should be avoided, and it should be ensured that the operation is carried out in a well-ventilated place.
Summary: Sieber Linker is a commonly used linker in organic synthesis, with stable chemical structure and good reproducibility. It is used in organic synthesis for ligation reactions, commonly used in pharmaceutical research, ligand synthesis and polymer synthesis. The preparation method is diverse, and the use needs to pay attention to safety matters.
1. Structural stability: Sieber Linker has a stable chemical structure and can remain stable under conventional experimental conditions.
2. Good reproducibility: The use of Sieber Linker can achieve a high degree of reproducibility, which is conducive to the reliability of the experimental results.
3. Easy synthesis: The method of preparing Sieber Linker is relatively simple, and the common synthesis tail can be used for the synthesis of different compounds.
Sieber Linker is mainly used for connection reactions in organic synthesis. It can link two molecules or compounds in the nucleophilic group and electron affinity group together to form a new chemical bond. This linkage reaction is widely used in pharmaceutical research, ligand synthesis and polymer synthesis.
There are many methods for preparing Sieber Linker. Common methods include nucleophilic substitution, condensation reaction and electrophilic substitution. The specific preparation method can be selected according to the desired ligation reaction and the structure of the target compound.
When using Sieber Linker, you need to pay attention to some safety matters. It may be toxic to a certain extent, so proper precautions such as gloves, goggles and outside laboratory operations are required during operation. In addition, direct contact with the skin and inhalation of its gas or dust should be avoided, and it should be ensured that the operation is carried out in a well-ventilated place.
Summary: Sieber Linker is a commonly used linker in organic synthesis, with stable chemical structure and good reproducibility. It is used in organic synthesis for ligation reactions, commonly used in pharmaceutical research, ligand synthesis and polymer synthesis. The preparation method is diverse, and the use needs to pay attention to safety matters.
Last Update：2024-04-09 21:32:40
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View History
6-Hydroxy-3-Fluorone
Sulphur Blue 15
Oils,patchouli
Metachrome yellow
MALONIC MONONITRILE
DIBENZOYL-D-TARTARIC ACID
niaproof type 8
4-bromophenyl butyrate
Vinylformic acid
Methyl chloride
Sulphur Blue 15
Oils,patchouli
Metachrome yellow
MALONIC MONONITRILE
DIBENZOYL-D-TARTARIC ACID
niaproof type 8
4-bromophenyl butyrate
Vinylformic acid
Methyl chloride