5-Sulfo-8-hydroxyquinoline
8-Hydroxyquinoline-5-sulfonic acid
CAS: 84-88-8
Molecular Formula: C9H7NO4S
5-Sulfo-8-hydroxyquinoline - Names and Identifiers
5-Sulfo-8-hydroxyquinoline - Physico-chemical Properties
| Molecular Formula | C9H7NO4S |
| Molar Mass | 225.22 |
| Density | 1.4899 (rough estimate) |
| Melting Point | 311-313°C |
| Appearance | Crystalline powder |
| Color | yellow to green |
| Merck | 4844 |
| pKa | pK1:4.092(＋1);pK2:8.776(0) (25°C) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.5364 (estimate) |
| MDL | MFCD00006795 |
| Physical and Chemical Properties | Pale yellow needle crystal or crystalline powder. Melting point 213 ℃ (decomposition). Easily soluble in water, slightly soluble in organic solvents. |
| Use | Used as a pharmaceutical Intermediate |
5-Sulfo-8-hydroxyquinoline - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36 - Irritating to the eyes R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| UN IDs | 2811 |
| WGK Germany | 3 |
| RTECS | VC2570000 |
| HS Code | 29334990 |
| Hazard Class | 6.1(b) |
| Packing Group | III |
5-Sulfo-8-hydroxyquinoline - Reference
| Reference Show more | 1. [IF=5.833] Qin Ying et al."Boron carbon oxynitride quantum dots-based ratio fluorescent nanoprobe assisted with smartphone for visualization detection of phosphate."MICROCHIMICA ACTA. 2022 Jun;189(6):1-10 |
5-Sulfo-8-hydroxyquinoline - Reference Information
| chemical properties | light yellow needle crystal or crystalline powder. Melting point 213 ℃ (decomposition). Easily soluble in water, slightly soluble in organic solvents. |
| use | used as an intermediate in organic synthesis and an analytical reagent. used as pharmaceutical intermediate pre-column and post-column derivatization reagent for fluorescence detection of metal ions |
| production method | obtained by sulfonation of 8-hydroxyquinoline. The fuming sulfuric acid was cooled to below 10 ℃ under stirring, and 8-hydroxyquinoline was gradually added to keep the temperature below 15 ℃. After adding, the temperature is increased, and the reaction is stirred below 30 ℃ for 5 hours. Leave overnight. The next day, put the reaction liquid into 8-10 times the amount of water (calculated by 8-hydroxyquinoline), control the temperature to 60 ℃, precipitate crystallization, and then leave it overnight. Filtration, washing and drying at 100 ℃ to obtain 8-hydroxyquinoline-5-sulfonic acid. 87% yield. |
| NIST chemical information | The information is: webbook.nist.gov provides (external link) |
| EPA chemical information | The information is: offered by ofmpub.epa.gov (external link) |
Last Update：2024-04-10 22:29:15
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View History
5-Sulfo-8-hydroxyquinoline
2-(2-Fluorophenyl)ethyl isocyanide
哒净硫磷
438463-31-1
573715-07-8
2-氰乙酰胺
375363-23-8
脱水钾明矾
Lemongrass Oil
134877-62-6
2-(2-Fluorophenyl)ethyl isocyanide
哒净硫磷
438463-31-1
573715-07-8
2-氰乙酰胺
375363-23-8
脱水钾明矾
Lemongrass Oil
134877-62-6