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5,8-dihydroxy-1,4-naphthoquinone

5,8-dihydroxy-1,4-naphthoquinone

CAS: 475-38-7

Molecular Formula: C10H6O4

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5,8-dihydroxy-1,4-naphthoquinone - Names and Identifiers

Name 5,8-dihydroxy-1,4-naphthoquinone
Synonyms 475-38-7
Naphthazarine
5,8-Dihydroxynaphthoquinone
5,8-dihydroxy-4-naphthoquinone
,8-Dihydroxy-[1,4]naphthoquinone
5,8-dihydroxy-4-naphthalenedione
5,8-dihydroxy-1,4-naphthoquinone
,8-Dihydroxy-1,4-naphthalenedione
5,8-dihydroxynaphthalene-1,4-dione
1,4-Naphthoquinone, 5,8-dihydroxy-
1,4-naphthalenedione, 5,8-dihydroxy-
2,3-Dihydro-1,4,5,8-naphthalenetetrone
CAS 475-38-7
EINECS 207-495-4
InChI InChI=1/C10H6O4/c11-5-1-2-6(12)10-8(14)4-3-7(13)9(5)10/h1-4,11-12H

5,8-dihydroxy-1,4-naphthoquinone - Physico-chemical Properties

Molecular FormulaC10H6O4
Molar Mass190.15
Density1.3366 (rough estimate)
Melting Point220-230°C(lit.)
Boling Point285.64°C (rough estimate)
Flash Point269.2°C
Water SolubilitySoluble in water (5520 mg/L 25.).
Vapor Presure1.51E-10mmHg at 25°C
Appearancepowder to crystaline
ColorDark red to Brown
BRN880561
pKa6.98±0.20(Predicted)
Storage ConditionSealed in dry,Room Temperature
Refractive Index1.5280 (estimate)
MDLMFCD00001685

5,8-dihydroxy-1,4-naphthoquinone - Risk and Safety

Hazard SymbolsXi - Irritant
Irritant
Risk Codes36/37/38 - Irritating to eyes, respiratory system and skin.
Safety DescriptionS22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
S37/39 - Wear suitable gloves and eye/face protection
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany3
RTECSQL7970000

5,8-dihydroxy-1,4-naphthoquinone - Reference Information

NIST chemical information Information provided by: webbook.nist.gov (external link)
Biological activity Naphthazarin (DHNQ) is a naturally occurring compound that is effective through a variety of cellular mechanisms, including oxidative stress, mitochondrial apoptosis inducing factor (AIF) activation, Microtubule depolymerization, interference with lysosomal function and p53-dependent p21 activation. Naphthazarin triggers apoptosis (apoptosis) and has anti-tumor effect.
Last Update:2024-04-09 15:16:50
5,8-dihydroxy-1,4-naphthoquinone
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