452-11-9
3-fluoro-4-methoxyphenol
CAS: 452-11-9
Molecular Formula: C7H7FO2
452-11-9 - Names and Identifiers
| Name | 3-fluoro-4-methoxyphenol |
| Synonyms | 3-FLUORO-4-METHOXYPHENOL 3-fluoro-4-methoxyphenol 2-Fluoro-4-hydroxyanisole Phenol, 3-fluoro-4-methoxy- 4-Aminomethyl-4-(3-bromo-phenyl)-piperidine-1-carboxylic acid tert-butyl ester |
| CAS | 452-11-9 |
| InChI | InChI=1/C7H7FO2/c1-10-7-3-2-5(9)4-6(7)8/h2-4,9H,1H3 |
452-11-9 - Physico-chemical Properties
| Molecular Formula | C7H7FO2 |
| Molar Mass | 142.13 |
| Density | 1.224±0.06 g/cm3(Predicted) |
| Melting Point | 54-55 °C |
| Boling Point | 248.2±20.0 °C(Predicted) |
| Flash Point | 121.424°C |
| Vapor Presure | 0.016mmHg at 25°C |
| Appearance | White-like solid |
| pKa | 9.46±0.18(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.512 |
452-11-9 - Introduction
3-fluoro-4-methoxyphenol is an organic compound with the chemical formula C7H7FO2.
Nature:
3-fluoro-4-methoxyphenol is a white crystalline solid with a distinctive phenol odor. It has a melting point of 30-32 degrees Celsius and a boiling point of 83 degrees Celsius. The compound is soluble in organic solvents such as alcohols, ethers and ketones, but hardly soluble in water.
Use:
3-fluoro-4-methoxyphenol is often used as an important intermediate in organic synthesis. It can be used to prepare compounds such as pharmaceuticals, dyes and pesticides. In addition, it can also be used as a rubber antioxidant and preservative.
Preparation Method:
3-fluoro-4-methoxyphenol can generate p-methoxyphenol trifluoromethanesulfonic acid ester by the reaction of phenol and trifluoromethanesulfonic acid anhydride, and then obtain the target product by hydrolysis.
Safety Information:
3-fluoro-4-methoxyphenol has low toxicity, but it is still necessary to pay attention to safe operation. It may be irritating to the eyes and skin, and has some corrosiveness. When using, avoid inhaling its dust or solution, and ensure good ventilation conditions. Avoid contact with oxidants and combustibles during handling and storage. In the case of accidental contact, immediately flush the affected area with plenty of water and seek medical help.
Nature:
3-fluoro-4-methoxyphenol is a white crystalline solid with a distinctive phenol odor. It has a melting point of 30-32 degrees Celsius and a boiling point of 83 degrees Celsius. The compound is soluble in organic solvents such as alcohols, ethers and ketones, but hardly soluble in water.
Use:
3-fluoro-4-methoxyphenol is often used as an important intermediate in organic synthesis. It can be used to prepare compounds such as pharmaceuticals, dyes and pesticides. In addition, it can also be used as a rubber antioxidant and preservative.
Preparation Method:
3-fluoro-4-methoxyphenol can generate p-methoxyphenol trifluoromethanesulfonic acid ester by the reaction of phenol and trifluoromethanesulfonic acid anhydride, and then obtain the target product by hydrolysis.
Safety Information:
3-fluoro-4-methoxyphenol has low toxicity, but it is still necessary to pay attention to safe operation. It may be irritating to the eyes and skin, and has some corrosiveness. When using, avoid inhaling its dust or solution, and ensure good ventilation conditions. Avoid contact with oxidants and combustibles during handling and storage. In the case of accidental contact, immediately flush the affected area with plenty of water and seek medical help.
Last Update：2024-04-09 20:52:54
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