4-chloro-2-fluroaniline
2,3,4-Trifluoronitrobenzene
CAS: 771-69-7
Molecular Formula: C6H2F3NO2
4-chloro-2-fluroaniline - Names and Identifiers
| Name | 2,3,4-Trifluoronitrobenzene |
| Synonyms | 4-chloro-2-fluroaniline 3,4,5 TRIFLUORONITROBENZEN 2,3,4-Dichloronitrobenzene 2,3,4-Trifluornitrobenzene 2,3,4-Trifluoronitrobenzene 2,3,4-TRIFLUORONITROBRNZENE 2,3,4-trifluoro nitrobenzene 1,2,3-Trifluoro-4-nitrobenzene 1-nitro-2,3,4-trifluorobenzene 2,3,4-TRIFLUORONITROBENZENEOFLOXACIN |
| CAS | 771-69-7 |
| EINECS | 212-238-4 |
| InChI | InChI=1/C7H2Cl2F4/c8-4-1-3(7(11,12)13)2-5(9)6(4)10/h1-2H |
4-chloro-2-fluroaniline - Physico-chemical Properties
| Molecular Formula | C6H2F3NO2 |
| Molar Mass | 177.08 |
| Density | 1.541 g/mL at 25 °C (lit.) |
| Boling Point | 92 °C/20 mmHg (lit.) |
| Flash Point | 200°F |
| Vapor Presure | 2.4mmHg at 25°C |
| Appearance | clear liquid |
| Specific Gravity | 1.541 |
| Color | Light yellow to Yellow to Orange |
| BRN | 2449746 |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | n20/D 1.492(lit.) |
| Physical and Chemical Properties | trait light yellow liquid. |
| Use | It is used as an intermediate of ofloxacin, lomefloxacin and norfloxacin |
4-chloro-2-fluroaniline - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S24/25 - Avoid contact with skin and eyes. |
| UN IDs | UN2810 |
| WGK Germany | 3 |
| HS Code | 29042090 |
| Hazard Note | Irritant |
| Hazard Class | 6.1 |
| Packing Group | III |
4-chloro-2-fluroaniline - Upstream Downstream Industry
| Raw Materials | 2,5-Dichloroaniline 2,6-Dichloroaniline Sulfanilamide Potassium fluoride Fluoroboric acid Nitric acid Hydrochloric acid |
| Downstream Products | Lomefloxacin hydrochloride |
4-chloro-2-fluroaniline - Nature
Open Data Verified Data
light yellow oily liquid. The boiling point is 92 ℃(2. 7kPa,20mmHg), the relative density is 1.541, the refractive index is 1. 4920, and the flash point is 93 ℃. This product is irritating.
Last Update：2025-06-10 22:55:16
4-chloro-2-fluroaniline - Preparation Method
Open Data Verified Data
2, 6-chloroaniline was prepared by Schiemann reaction, nitration and fluorination.
Last Update：2022-01-01 10:44:38
4-chloro-2-fluroaniline - Application
Open Data Verified Data
This product is mainly used for the synthesis of a new generation of fluoroquinolone antibacterial agent, ofloxacin. It can also be used for the synthesis of quinonic acid antibacterial drug lomefloxacin and the like.
Last Update：2025-08-19 16:24:40
4-chloro-2-fluroaniline - Safety
Open Data Verified Data
The packaging is lined with plastic iron drum, 50kg/barrel.
Last Update：2022-01-01 10:44:39
4-chloro-2-fluroaniline - Reference Information
| Use | used as intermediate of ofloxacin, lomefloxacin and norfloxacin used as drug, this product is mainly used for the synthesis of a new generation of fluoroquinolone antibacterial agent, ofloxacin. It can also be used for the synthesis of quinonic acid antibacterial drug lomefloxacin and the like. |
| production method | with 2, 6-dichloroaniline as raw material, it is prepared by Schiemann reaction, nitration and fluorination. |
Last Update：2024-04-09 02:00:11
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View History
4-chloro-2-fluroaniline
BOC-甘氨酰-甘氨酰-甘氨酸
ETHYL 4-CHLORO-2-METHYLTHIOPYRIMIDINE-5-CARBOXYLATE
双(三氟-2,4-戊二酮)镁(II)
Methyl p-methoxyphenylpropionate
1-sulfanyl-1H-benzimidazole
2,3- twochlorineisonicotinic acid
meso-四(4-羧基苯基)卟吩氯化铁
2-(2,4-dichlorophenyl)ethanaminium
BOC-甘氨酰-甘氨酰-甘氨酸
ETHYL 4-CHLORO-2-METHYLTHIOPYRIMIDINE-5-CARBOXYLATE
双(三氟-2,4-戊二酮)镁(II)
Methyl p-methoxyphenylpropionate
1-sulfanyl-1H-benzimidazole
2,3- twochlorineisonicotinic acid
meso-四(4-羧基苯基)卟吩氯化铁
2-(2,4-dichlorophenyl)ethanaminium
Raw Materials for 4-chloro-2-fluroaniline
Downstream Products for 4-chloro-2-fluroaniline