4-Nitrophenetole
4-nitrophenetole
CAS: 100-29-8
Molecular Formula: C8H9NO3
4-Nitrophenetole - Names and Identifiers
| Name | 4-nitrophenetole |
| Synonyms | NSC 9812 AI3-00233 HSDB 5333 CCRIS 2333 BRN 0972473 4-Nitrophenetol p-Nitrophenetol 4-nitrophenetole p-Nitrophenetole 4-Nitrophenetole Phenetole, p-nitro- 4-Ethoxynitrobenzene p-Ethoxynitrobenzene 1-Ethoxy-4-nitrobenzene p-Nitrophenetol [German] Ethyl p-nitrophenyl ether Phenetole, p-nitro- (8CI) Benzene, 1-ethoxy-4-nitro- 4-06-00-01283 (Beilstein Handbook Reference) |
| CAS | 100-29-8 |
| EINECS | 202-837-9 |
| InChI | InChI=1/C8H9NO3/c1-2-12-8-5-3-7(4-6-8)9(10)11/h3-6H,2H2,1H3 |
4-Nitrophenetole - Physico-chemical Properties
| Molecular Formula | C8H9NO3 |
| Molar Mass | 167.162 |
| Density | 1.178g/cm3 |
| Melting Point | 56-60℃ |
| Boling Point | 283°C at 760 mmHg |
| Flash Point | 134.1°C |
| Vapor Presure | 0.00555mmHg at 25°C |
| Refractive Index | 1.534 |
4-Nitrophenetole - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
4-Nitrophenetole - Nature
Open Data Verified Data
light yellow crystals. Melting point 60 ℃(58 ℃), boiling point 283 ℃,112~115 ℃(0.4kPa), relative density of 1. 1176. Slightly soluble in water, cold ethanol and cold petroleum ether. Soluble in ether, soluble in hot ethanol and hot petroleum ether.
Last Update：2024-01-02 23:10:35
4-Nitrophenetole - Preparation Method
Open Data Verified Data
from p-nitrochlorobenzene and ethanol by etherification reaction. The p-nitrochlorobenzene and ethanol were added to the reaction vessel, the temperature was raised to 82 ° C., ethanol sodium hydroxide solution was added dropwise, and the reaction was carried out at 85-88 ° C. For 3 hours. The alkalinity of the reaction solution was reduced to less than 0.9%, and the temperature was lowered to 75 ° C., and the pH value was adjusted to 6.7~7 with concentrated hydrochloric acid. After standing and stratification, the oil layer is taken out and washed with water to remove sodium nitrophenolate. The oil layer is subjected to vacuum rectification, and the fraction of 214~218 ℃(2. 66~5.32kPa) is taken as the product.
Last Update：2022-01-01 10:50:32
4-Nitrophenetole - Use
Open Data Verified Data
used as an intermediate for drugs and dyes. In medicine for the synthesis of phenacetin.
Last Update：2022-01-01 10:50:32
4-Nitrophenetole - Safety
Open Data Verified Data
- This product is toxic. Inhalation and ingestion are harmful to health. Wear all-protective glasses, wear anti-virus penetration work clothes, and wear self-priming filter compound dust mask when exposed to dust.
- packaging using small opening steel barrel, screw mouth glass bottle, cover pressure mouth glass bottle, plastic bottle or metal barrel (can) outside the wood box. Store in a cool, ventilated warehouse. Keep away from fire and heat source, prevent direct sunlight, and seal the container. Light removal during handling.
Last Update：2022-01-01 10:50:33
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Product Name: *4-Nitrophenetole Visit Supplier Webpage Request for quotationCAS: 100-29-8
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
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