4-(Dimethylamino)phenol
4-(Dimethylamino)phenol
CAS: 619-60-3
Molecular Formula: C8H11NO
4-(Dimethylamino)phenol - Names and Identifiers
| Name | 4-(Dimethylamino)phenol |
| Synonyms | DMAP (antidote) 4-Dimethylaminophenol p-(Dimethylamino)phenol 4-(dimethylamino)phenol 4-(Dimethylamino)phenol Phenol,4-(diMethylaMino)- 4-N,N-DIMETHYLAMINOPHENOL N,N-Dimethyl-4-aminophenol Phenol, p-(dimethylamino)- Phenol, 4-(dimethylamino)- N,N-Dimethyl-p-hydroxyaniline p-Hydroxy-N,N-dimethylaniline |
| CAS | 619-60-3 |
| EINECS | 210-604-8 |
| InChI | InChI=1/C8H11NO.C2H2O4/c1-9(2)7-3-5-8(10)6-4-7;3-1(4)2(5)6/h3-6,10H,1-2H3;(H,3,4)(H,5,6) |
4-(Dimethylamino)phenol - Physico-chemical Properties
| Molecular Formula | C8H11NO |
| Molar Mass | 137.18 |
| Density | 1.089 |
| Melting Point | 138-141℃ |
| Boling Point | 260℃ |
| Flash Point | 136℃ |
| Vapor Presure | 0.00789mmHg at 25°C |
| pKa | 10.11±0.13(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| Refractive Index | 1.5560 (estimate) |
4-(Dimethylamino)phenol - Introduction
4-(Dimethylamino)phenol, chemical formula C8H11NO, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
- 4-(Dimethylamino)phenol is a colorless to pale yellow crystal or crystalline powder.
-It is soluble in solvents such as ethanol, ether and dichloromethane.
-It is an alkaline substance that can form hydrochloride.
-it can be substituted with acylating reagent reaction.
Use:
- 4-(Dimethylamino)phenol is often used as a reagent, catalyst and indicator for chemical reactions.
-It can be used in some important reactions in organic synthesis, such as Mannich reaction and nitro substitution reaction.
-It can also be used as a precursor for dyes and pigments, used in the dye industry and the preparation of fluorescent dyes.
Preparation Method:
- 4-(Dimethylamino)phenol can be obtained by reacting phenol with dimethylamine. The reaction conditions may be under basic conditions, for example using a base catalyst.
Safety Information:
- 4-(Dimethylamino)phenol is a toxic substance, should avoid inhalation and contact with skin.
-Wear protective gloves, goggles and protective clothing during use.
-Observe relevant safety regulations during storage and handling, and keep it away from ignition and oxidizing agents.
-If ingested or inhaled, seek medical attention immediately.
Nature:
- 4-(Dimethylamino)phenol is a colorless to pale yellow crystal or crystalline powder.
-It is soluble in solvents such as ethanol, ether and dichloromethane.
-It is an alkaline substance that can form hydrochloride.
-it can be substituted with acylating reagent reaction.
Use:
- 4-(Dimethylamino)phenol is often used as a reagent, catalyst and indicator for chemical reactions.
-It can be used in some important reactions in organic synthesis, such as Mannich reaction and nitro substitution reaction.
-It can also be used as a precursor for dyes and pigments, used in the dye industry and the preparation of fluorescent dyes.
Preparation Method:
- 4-(Dimethylamino)phenol can be obtained by reacting phenol with dimethylamine. The reaction conditions may be under basic conditions, for example using a base catalyst.
Safety Information:
- 4-(Dimethylamino)phenol is a toxic substance, should avoid inhalation and contact with skin.
-Wear protective gloves, goggles and protective clothing during use.
-Observe relevant safety regulations during storage and handling, and keep it away from ignition and oxidizing agents.
-If ingested or inhaled, seek medical attention immediately.
Last Update：2024-04-10 22:29:15
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