4,6-DIFLUOROINDOLINE-2,3-DIONE
4,6-DIFLUOROINDOLINE-2,3-DIONE
CAS: 126674-93-9
Molecular Formula: C8H3F2NO2
4,6-DIFLUOROINDOLINE-2,3-DIONE - Names and Identifiers
| Name | 4,6-DIFLUOROINDOLINE-2,3-DIONE |
| Synonyms | 4,6-DIFLUOROISATIN 4,6-DIFLUOROINDOLINE-2,3-DIONE 4,6-Difluoro-2,3-dioxoindoline 1H-Indole-2,3-dione, 4,6-difluoro- 4,6-difluoro-2,3-dihydro-1H-indole-2,3-dione 4,6-Difluoro isatin 4,6-Difluoro indole-2,3-dione |
| CAS | 126674-93-9 |
| InChI | InChI=1/C8H3F2NO2/c9-3-1-4(10)6-5(2-3)11-8(13)7(6)12/h1-2H,(H,11,12,13) |
4,6-DIFLUOROINDOLINE-2,3-DIONE - Physico-chemical Properties
| Molecular Formula | C8H3F2NO2 |
| Molar Mass | 183.11 |
| Density | 1.578 |
| pKa | 7.65±0.20(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.558 |
4,6-DIFLUOROINDOLINE-2,3-DIONE - Introduction
4,6-Difluoroisatin is an organic dye with the chemical formula C16H5F2N2O2. It is a dark red crystal, soluble in alcohol and ketone solvents, insoluble in water. The following is a description of the properties, uses, preparation methods and safety information of 4,6-difluoroisatin:
Nature:
1. Appearance: 4,6-difluoroisatin is a dark red crystal.
2. Solubility: Soluble in alcohol and ketone solvents, but insoluble in water.
3. Chromatography: It has certain recognition in thin layer chromatography and liquid chromatography and can be used for chemical analysis.
4. stability: stable at room temperature, but at high temperature, strong acid and alkali conditions will occur decomposition.
Use:
1. Dye: 4,6-difluoroindigo red is commonly used as a dye for textiles, leather and paint, etc. It has good light resistance, washing resistance and high temperature resistance.
2. biochemical reagents: due to its bright color and good stability, 4,6-difluoroisatin is often used as a biochemical reagent, for example, as a dye for DNA gel electrophoresis.
Preparation Method:
4,6-difluoroisatin can be obtained by fluorination reaction of nitrated isatin. Isatin was first dissolved in concentrated sulfuric acid, and then hydrogen fluoride and nitric acid were added to give 4,6-difluoroisatin after reaction.
Safety Information:
1. 4, 6-Difluoroisatin can cause eye and skin irritation and direct contact should be avoided.
2. Inhalation or accidental ingestion of 4,6-difluoroisatin will cause harm to the body, should avoid inhalation of dust and keep it properly to prevent accidental ingestion.
3. When using 4,6-difluoroisatin, pay attention to avoid contact with strong acids and strong bases and other chemicals to avoid dangerous reactions.
4. 4, 6-difluoroisatin should be stored in a dry, cool place, away from fire and flammable materials.
Nature:
1. Appearance: 4,6-difluoroisatin is a dark red crystal.
2. Solubility: Soluble in alcohol and ketone solvents, but insoluble in water.
3. Chromatography: It has certain recognition in thin layer chromatography and liquid chromatography and can be used for chemical analysis.
4. stability: stable at room temperature, but at high temperature, strong acid and alkali conditions will occur decomposition.
Use:
1. Dye: 4,6-difluoroindigo red is commonly used as a dye for textiles, leather and paint, etc. It has good light resistance, washing resistance and high temperature resistance.
2. biochemical reagents: due to its bright color and good stability, 4,6-difluoroisatin is often used as a biochemical reagent, for example, as a dye for DNA gel electrophoresis.
Preparation Method:
4,6-difluoroisatin can be obtained by fluorination reaction of nitrated isatin. Isatin was first dissolved in concentrated sulfuric acid, and then hydrogen fluoride and nitric acid were added to give 4,6-difluoroisatin after reaction.
Safety Information:
1. 4, 6-Difluoroisatin can cause eye and skin irritation and direct contact should be avoided.
2. Inhalation or accidental ingestion of 4,6-difluoroisatin will cause harm to the body, should avoid inhalation of dust and keep it properly to prevent accidental ingestion.
3. When using 4,6-difluoroisatin, pay attention to avoid contact with strong acids and strong bases and other chemicals to avoid dangerous reactions.
4. 4, 6-difluoroisatin should be stored in a dry, cool place, away from fire and flammable materials.
Last Update：2024-04-10 22:29:15
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