36160-82-4
4-(4-Fluorophenoxy)aniline
CAS: 36160-82-4
Molecular Formula: C12H10FNO
36160-82-4 - Names and Identifiers
| Name | 4-(4-Fluorophenoxy)aniline |
| Synonyms | AKOS B021931 ART-CHEM-BB B021931 TIMTEC-BB SBB009577 SALOR-INT L300837-1EA 4-(4-Fluorophenoxy)aniline 4-(4-FLUOROPHENOXY)ANILINE 4-(4-FLUOROPHENOXY)BENZENAMINE 4-Amino-4'-fluorodiphenyl ether Benzenamine, 4-(4-fluorophenoxy)- |
| CAS | 36160-82-4 |
| InChI | InChI=1/C12H10FNO/c13-9-1-5-11(6-2-9)15-12-7-3-10(14)4-8-12/h1-8H,14H2 |
36160-82-4 - Physico-chemical Properties
| Molecular Formula | C12H10FNO |
| Molar Mass | 203.22 |
| Density | 1.22g/cm3 |
| Melting Point | 58.9-60.4 |
| Boling Point | 317.2°C at 760 mmHg |
| Flash Point | 145.7°C |
| Vapor Presure | 0.00039mmHg at 25°C |
| Storage Condition | 2-8°C |
| Refractive Index | 1.599 |
36160-82-4 - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes |
| Safety Description | 36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
36160-82-4 - Introduction
4-(4-Fluorophenoxy)aniline is an organic compound with the chemical formula C12H10FNO. The following is a description of the relevant properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: colorless to light yellow crystal
-Melting point: 82-85 degrees Celsius
-Boiling point: 386 degrees Celsius (estimated by approximation)
-Solubility: Soluble in organic solvents such as ethanol, chloroform and ether
Use:
- 4-(4-Fluorophenoxy)aniline is an important organic synthesis intermediate, which is widely used in pesticide, medicine, dye and other fields.
-It can be used to synthesize compounds containing aniline structure, with potential biological activity and function.
Preparation Method:
- 4-(4-Fluorophenoxy)aniline can be prepared by the reaction of aniline and 4-fluorophenol.
-First, dissolve aniline and sodium carbonate in the solvent, then add 4-fluorophenol, and heat the reaction.
-Finally, the product is purified by crystallization or column chromatography.
Safety Information:
- 4-(4-Fluorophenoxy)aniline can cause eye and skin irritation and should avoid skin contact and inhalation.
-Wear appropriate personal protective equipment such as chemical goggles, protective gloves and gas masks during use.
-When storing and handling the compound, be careful to avoid contact with oxidants and strong acids to avoid potentially dangerous reactions.
-in the use of the process, to strictly abide by the laboratory safety procedures, and properly dispose of waste.
Nature:
-Appearance: colorless to light yellow crystal
-Melting point: 82-85 degrees Celsius
-Boiling point: 386 degrees Celsius (estimated by approximation)
-Solubility: Soluble in organic solvents such as ethanol, chloroform and ether
Use:
- 4-(4-Fluorophenoxy)aniline is an important organic synthesis intermediate, which is widely used in pesticide, medicine, dye and other fields.
-It can be used to synthesize compounds containing aniline structure, with potential biological activity and function.
Preparation Method:
- 4-(4-Fluorophenoxy)aniline can be prepared by the reaction of aniline and 4-fluorophenol.
-First, dissolve aniline and sodium carbonate in the solvent, then add 4-fluorophenol, and heat the reaction.
-Finally, the product is purified by crystallization or column chromatography.
Safety Information:
- 4-(4-Fluorophenoxy)aniline can cause eye and skin irritation and should avoid skin contact and inhalation.
-Wear appropriate personal protective equipment such as chemical goggles, protective gloves and gas masks during use.
-When storing and handling the compound, be careful to avoid contact with oxidants and strong acids to avoid potentially dangerous reactions.
-in the use of the process, to strictly abide by the laboratory safety procedures, and properly dispose of waste.
Last Update：2024-04-09 21:01:54
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