352534-79-3
2-Fluoro-5-formylbenzeneboronic acid
CAS: 352534-79-3
Molecular Formula: C7H6BFO3
352534-79-3 - Names and Identifiers
352534-79-3 - Physico-chemical Properties
| Molecular Formula | C7H6BFO3 |
| Molar Mass | 167.93 |
| Density | 1.33g/cm3 |
| Melting Point | 168-171°C |
| Boling Point | 360.2°C at 760 mmHg |
| Flash Point | 171.7°C |
| Vapor Presure | 8.11E-06mmHg at 25°C |
| Storage Condition | 2-8℃ |
| Sensitive | Air Sensitive |
| Refractive Index | 1.524 |
| MDL | MFCD03095100 |
352534-79-3 - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R40 - Limited evidence of a carcinogenic effect R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S22 - Do not breathe dust. |
| Hazard Class | IRRITANT |
352534-79-3 - Introduction
Acid is an organic compound with the chemical formula C7H6BFO3. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: white to yellowish solid;
-Melting point: about 100-105 degrees Celsius;
-Solubility: Soluble in water, soluble in organic solvents such as ethanol, dimethyl sulfoxide and dichloromethane;
-Molecular weight: 169.93g/mol.
Use:
-acid is commonly used in the field of organic synthesis, as an important organic synthesis intermediate;
-It can be used to construct C- C bonds and C- X bonds, such as for the synthesis of heterocyclic compounds, fluorescent dyes and drugs;
-must acid can also be used for catalyst preparation and catalytic reaction.
Preparation Method:
There are two main preparation methods for acid:
1. benzoylphenylboronic acid is obtained by the reaction of benzoyl fluoride and sodium phenylborate, and then hydrogen fluoride gas is used to act on benzoylphenylboronic acid to obtain acid.
2. Through the reaction of bromo 2-fluorobenzene and formylboronic acid diethyl ester, reduction is generated to acid.
Safety Information:
-the acid should be careful to avoid contact with skin and eyes during operation;
-Avoid inhaling dust or gas, and it is recommended to operate in a well-ventilated environment;
-storage should be sealed, away from fire and oxidant;
-If ingested or inhaled, seek medical attention immediately. In case of skin contact, flush with plenty of water and seek medical help.
Nature:
-Appearance: white to yellowish solid;
-Melting point: about 100-105 degrees Celsius;
-Solubility: Soluble in water, soluble in organic solvents such as ethanol, dimethyl sulfoxide and dichloromethane;
-Molecular weight: 169.93g/mol.
Use:
-acid is commonly used in the field of organic synthesis, as an important organic synthesis intermediate;
-It can be used to construct C- C bonds and C- X bonds, such as for the synthesis of heterocyclic compounds, fluorescent dyes and drugs;
-must acid can also be used for catalyst preparation and catalytic reaction.
Preparation Method:
There are two main preparation methods for acid:
1. benzoylphenylboronic acid is obtained by the reaction of benzoyl fluoride and sodium phenylborate, and then hydrogen fluoride gas is used to act on benzoylphenylboronic acid to obtain acid.
2. Through the reaction of bromo 2-fluorobenzene and formylboronic acid diethyl ester, reduction is generated to acid.
Safety Information:
-the acid should be careful to avoid contact with skin and eyes during operation;
-Avoid inhaling dust or gas, and it is recommended to operate in a well-ventilated environment;
-storage should be sealed, away from fire and oxidant;
-If ingested or inhaled, seek medical attention immediately. In case of skin contact, flush with plenty of water and seek medical help.
Last Update：2024-04-09 15:17:57
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View History
352534-79-3
901113-68-6
34171-37-4
壬醛 标准品
三己基氧化膦
西替利嗪
O-ALLYLCYCLOHEXANONE
大花旋覆花素
聚酰胺树脂
Z-ASP-GLU-VAL-ASP-AFC: Z-DEVD-AFC
901113-68-6
34171-37-4
壬醛 标准品
三己基氧化膦
西替利嗪
O-ALLYLCYCLOHEXANONE
大花旋覆花素
聚酰胺树脂
Z-ASP-GLU-VAL-ASP-AFC: Z-DEVD-AFC