351500-12-4

351500-12-4 - Names and Identifiers

Name	1H-Indole-1-carboxylic acid, 5-(trifluoromethyl)-, 1,1-dimethylethyl ester
Synonyms	tert-Butyl 5-(trifluoromethyl)-1H-indole-1-carboxylate 1H-Indole-1-carboxylic acid, 5-(trifluoromethyl)-, 1,1-dimethylethyl ester 1H-Indole-1-carboxylic acid, 5-(trifluoroMethyl)-, 1,1-diMethylethyl ester
CAS	351500-12-4

351500-12-4 - Physico-chemical Properties

Molecular Formula	C14H14F3NO2
Molar Mass	285.26
Storage Condition	Room Temprature

351500-12-4 - Introduction

1H-Indole-1-carboxylic acid, 5-(trifluoromethyl)-, 1,1-dimethylethyl ester is a chemical substance whose chemical name is 1H-Indole-1-carboxylic acid, 5-(trifluoromethyl)-, 1,1-dimethylethyl ester. The following is a description of the nature, use, preparation and safety information of the substance:

1. nature:
-Appearance: 1H-Indole-1-carboxylic acid, 5-(trifluoromethyl)-, 1,1-dimenthylethyl ester is a white solid.
-Molecular formula: C16H16F3NO2
-Molecular weight: 319.3g/mol
-Melting point: about 78-80 degrees Celsius
-Boiling point: about 406 degrees Celsius

2. use:
- 1H-Indole-1-carboxylic acid, 5-(trifluoromethyl)-, 1,1-dimethylethyl ester is commonly used as an intermediate in organic synthesis.
-It can be used to synthesize drugs, pesticides, dyes and other organic compounds.

3. Preparation method:
The preparation of-1H-Indole-1-carboxylic acid, 5-(trifluoromethyl)-, 1,1-dimethylethyl ester can be achieved by a variety of methods, one of which is through Indole and trifluoromethyl thionyl chloride Reaction, and then completely esterify the resulting product with N-Boc-1-benzyl-1H-indazole-4-isopropyl.

4. Safety Information:
- 1H-Indole-1-carboxylic acid, 5-(trifluoromethyl)-, 1,1-dimenthylethyl ester has limited toxicity studies, so specific toxicity and risk data are not clear.
-Use and handle the compound in accordance with safe laboratory practices, such as wearing appropriate protective equipment (e. g. gloves, goggles).
-During handling and storage, it should be separated from incompatible substances and avoid contact with fire and high temperature.

Last Update：2024-04-09 20:49:11