332884-21-6
4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butanoic acid
CAS: 332884-21-6
Molecular Formula: C12H16N2O2
332884-21-6 - Names and Identifiers
| Name | 4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butanoic acid |
| Synonyms | 5,6,7,8-Tetrahydro-1,8-naphthyridin-2-butyric acid 5,6,7,8-Tetrahydro-1,8-Naphthyridin-2-butyric acid 1,8-Naphthyridine-2-butanoic acid, 5,6,7,8-tetrahydro- 4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butanoic acid 4-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)butanoic acid 5,6,7,8-Tetrahydro-1,8-Naphthyridin-2-butyric acid hydrochloride 4-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)butanoic acid hydrochloride |
| CAS | 332884-21-6 |
| InChI | InChI=1/C12H16N2O2/c15-11(16)5-1-4-10-7-6-9-3-2-8-13-12(9)14-10/h6-7H,1-5,8H2,(H,13,14)(H,15,16) |
332884-21-6 - Physico-chemical Properties
| Molecular Formula | C12H16N2O2 |
| Molar Mass | 220.27 |
| Density | 1.184g/cm3 |
| Boling Point | 427.267°C at 760 mmHg |
| Flash Point | 212.204°C |
| Vapor Presure | 0mmHg at 25°C |
| Refractive Index | 1.561 |
332884-21-6 - Introduction
4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)-butanoic acid is an organic compound with the chemical formula C14H19NO2. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White crystalline powder or solid.
-Solubility: It is soluble in absolute ethanol, ether and chloroform, slightly soluble in water.
-Melting point: The compound has a high melting point, about 165-170°C.
Use:
-Pharmaceutical field: 4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butanoic acid is a drug intermediate that can be used to synthesize various drug compounds, such as anti-cancer drugs.
Method:
A commonly used preparation method is synthesis by the following steps:
1. First, 5,6,7,8-tetrahydro-1,8-naphthyridine and bromobutyrate are reacted to give 4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butanoic acid butyl ester.
2. Then, the ester compound is hydrolyzed with potassium hydroxide (KOH) to obtain 4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butanoic acid.
Safety Information:
-The toxicity information of this compound is limited, so it should be handled with care. Health and safety considerations require compliance with laboratory standards and operating procedures.
-During use, avoid contact with skin, eyes and mucous membranes to avoid irritation and damage.
-Appropriate precautions should be followed when handling the compound, using gloves, lab coats and goggles.
-When storing and handling the compound, care should be taken to avoid contact with oxidants and combustibles to prevent fire or explosion.
Nature:
-Appearance: White crystalline powder or solid.
-Solubility: It is soluble in absolute ethanol, ether and chloroform, slightly soluble in water.
-Melting point: The compound has a high melting point, about 165-170°C.
Use:
-Pharmaceutical field: 4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butanoic acid is a drug intermediate that can be used to synthesize various drug compounds, such as anti-cancer drugs.
Method:
A commonly used preparation method is synthesis by the following steps:
1. First, 5,6,7,8-tetrahydro-1,8-naphthyridine and bromobutyrate are reacted to give 4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butanoic acid butyl ester.
2. Then, the ester compound is hydrolyzed with potassium hydroxide (KOH) to obtain 4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butanoic acid.
Safety Information:
-The toxicity information of this compound is limited, so it should be handled with care. Health and safety considerations require compliance with laboratory standards and operating procedures.
-During use, avoid contact with skin, eyes and mucous membranes to avoid irritation and damage.
-Appropriate precautions should be followed when handling the compound, using gloves, lab coats and goggles.
-When storing and handling the compound, care should be taken to avoid contact with oxidants and combustibles to prevent fire or explosion.
Last Update：2024-04-09 21:01:54
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Product Name: 5,6,7,8-TETRAHYDRO-1,8-NAPHTHYRIDIN-2-BUTYRIC ACID Visit Supplier Webpage Request for quotationCAS: 332884-21-6
Tel: +86-400-900-4166
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