33284-21-8
3-(Trifluoroacetyl)pyridine
CAS: 33284-21-8
Molecular Formula: C7H4F3NO
33284-21-8 - Names and Identifiers
33284-21-8 - Physico-chemical Properties
| Molecular Formula | C7H4F3NO |
| Molar Mass | 175.11 |
| Density | 1.341±0.06 g/cm3(Predicted) |
| Boling Point | 197.9±35.0 °C(Predicted) |
| Flash Point | 73.506°C |
| Vapor Presure | 0.369mmHg at 25°C |
| pKa | 1?+-.0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.446 |
33284-21-8 - Introduction
3-(Trifluoroacetyl)pyridine(3-(Trifluoroacetyl)pyridine) is an organic compound with the chemical formula C7H4F3NO. The following is a detailed description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 3-(Trifluoroacetyl)pyridine is a colorless to light yellow liquid.
-Melting point: The melting point of this compound is about -31 ° C(-23.8 ° F).
-Boiling point: Its boiling point is about 116-118 ° C(241.4-244.4 ° F).
-Density: The density of 3-(Trifluoroacetyl)pyridine is about 1.41 g/cm ³.
-Solubility: It can be dissolved in many organic solvents (such as dimethylformamide, dichloromethane).
Use:
- 3-(Trifluoroacetyl)pyridine is commonly used as catalyst, intermediate and ligand in organic synthesis.
-It can be used to synthesize fluorine-containing organic compounds, such as the synthesis of fluorine-containing drugs, pesticides and dyes.
-The compound can also be used as an anti-tumor drug in tumor treatment.
Method:
- 3-(Trifluoroacetyl)pyridine can be prepared by reacting 3-carbonylpyridine with Trifluoroacetyl chloride.
-The usual preparation method involves dissolving 3-carbonylpyridine in an organic solvent, then slowly adding trifluoroacetyl chloride Dropwise and heating to react, and finally separating the organic layer with water and distilling to obtain the product.
Safety Information:
-Since 3-(Trifluoroacetyl)pyridine is an organic compound, it should be handled with caution and avoid direct contact with skin and eyes.
-During operation, adequate ventilation should be provided and appropriate protective gloves and safety glasses should be worn.
-In case of accidental contact or inhalation, rinse immediately with water and seek medical help.
-The compound should also be stored in a sealed container, away from fire and oxidizing agents.
-Please fully understand the safety data sheet (MSDS) and laboratory procedures for the compound before use.
Nature:
-Appearance: 3-(Trifluoroacetyl)pyridine is a colorless to light yellow liquid.
-Melting point: The melting point of this compound is about -31 ° C(-23.8 ° F).
-Boiling point: Its boiling point is about 116-118 ° C(241.4-244.4 ° F).
-Density: The density of 3-(Trifluoroacetyl)pyridine is about 1.41 g/cm ³.
-Solubility: It can be dissolved in many organic solvents (such as dimethylformamide, dichloromethane).
Use:
- 3-(Trifluoroacetyl)pyridine is commonly used as catalyst, intermediate and ligand in organic synthesis.
-It can be used to synthesize fluorine-containing organic compounds, such as the synthesis of fluorine-containing drugs, pesticides and dyes.
-The compound can also be used as an anti-tumor drug in tumor treatment.
Method:
- 3-(Trifluoroacetyl)pyridine can be prepared by reacting 3-carbonylpyridine with Trifluoroacetyl chloride.
-The usual preparation method involves dissolving 3-carbonylpyridine in an organic solvent, then slowly adding trifluoroacetyl chloride Dropwise and heating to react, and finally separating the organic layer with water and distilling to obtain the product.
Safety Information:
-Since 3-(Trifluoroacetyl)pyridine is an organic compound, it should be handled with caution and avoid direct contact with skin and eyes.
-During operation, adequate ventilation should be provided and appropriate protective gloves and safety glasses should be worn.
-In case of accidental contact or inhalation, rinse immediately with water and seek medical help.
-The compound should also be stored in a sealed container, away from fire and oxidizing agents.
-Please fully understand the safety data sheet (MSDS) and laboratory procedures for the compound before use.
Last Update：2024-04-09 21:04:16
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