| Name | 3-hydroxyphthalic anhydride |
| Synonyms | Nsc 80858 Brn 0135783 3-hydroxy-phthalicanhydrid 3-HYDROXYPHTHALIC ANHYDRIDE 3-hydroxyphthalic anhydride 4-hydroxy-3-isobenzofurandione 3-HYDROXYPHTHALIC ACID ANHYDRIDE 4-HYDROXY-ISOBENZOFURAN-1,3-DIONE 1,3-Isobenzofurandione, 4-hydroxy- |
| CAS | 37418-88-5 |
| InChI | InChI=1/C8H4O4/c9-5-3-1-2-4-6(5)8(11)12-7(4)10/h1-3,9H |
| InChIKey | CCTOEAMRIIXGDJ-UHFFFAOYSA-N |
| Molecular Formula | C8H4O4 |
| Molar Mass | 164.12 |
| Density | 1.624±0.06 g/cm3(Predicted) |
| Melting Point | 199-202 °C (lit.) |
| Boling Point | 365.4±25.0 °C(Predicted) |
| Flash Point | 160.2°C |
| Solubility | Acetonitrile (Slightly), DMSO (Slightly) |
| Vapor Presure | 7.47E-06mmHg at 25°C |
| Appearance | Powder |
| Color | White to beige |
| BRN | 135783 |
| pKa | 6.25±0.20(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Stability | Hygroscopic |
| Refractive Index | 1.666 |
| Hazard Symbols | Xi - Irritant![]() |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| RTECS | TI3300000 |
| FLUKA BRAND F CODES | 21 |
| HS Code | 29182900 |
| Reference Show more | 1. [IF=3.205] Han Fu et al."Preparation of magnetic molecularly imprinted polymer for selective identification of patulin in juice."J Chromatogr B. 2020 May;1145:122101 |
| Use | 3-hydroxyphthalic anhydride is used to synthesize 3-hydroxyphthalic anhydride-modified human serum albumin, which is used as a microbicide used to prevent HIV Sexual transmission has high efficacy. It can also be used as a reagent for the organic synthesis of other compounds, including thalidomide-derived NF-κB inhibitors. 3-hydroxyphthalic anhydride is used to synthesize 3-hydroxyphthalic anhydride modified human serum albumin. It has high bactericidal power and can prevent the sexual transmission of HIV. It can also be used as a reagent for the organic synthesis of other compounds, including thalidomide-derived NF-κB inhibitors. |
| application | 3-hydroxyphenyldianhydride is an organic synthesis intermediate and a pharmaceutical intermediate, which can be used in the organic synthesis process in laboratory research and development and the chemical and pharmaceutical synthesis process. |