3-FLUORO-4-METHYLPYRIDINE
3-Fluoro-4-methylpyridine
CAS: 399-88-2
Molecular Formula: C6H6FN
3-FLUORO-4-METHYLPYRIDINE - Names and Identifiers
3-FLUORO-4-METHYLPYRIDINE - Physico-chemical Properties
| Molecular Formula | C6H6FN |
| Molar Mass | 111.12 |
| Density | 1.08 g/cm |
| Boling Point | 135,6 C |
| Appearance | Liquid |
| Color | Colorless to pale yellow |
| pKa | 3.48±0.18(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1,479 |
3-FLUORO-4-METHYLPYRIDINE - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| UN IDs | 1993 |
| Hazard Class | 3 |
| Packing Group | Ⅲ |
3-FLUORO-4-METHYLPYRIDINE - Introduction
3-Fluoro-4-methylpyrridine is an organic compound with the chemical formula C6H6FN, structurally substituted with a methyl group and a fluorine atom on the number 4 carbon in the pyridine molecule. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: colorless transparent liquid
-Melting point:-25°C
-Boiling point: 119-120°C
-Density: 1.13 g/mL(25°C)
-Solubility: Soluble in alcohol and ether solvents, insoluble in water.
Use:
-3-Fluoro-4-methylpyrridine is an important organic synthesis intermediate, commonly used in drug synthesis and pesticide synthesis. It can be used as a starting material for the synthesis of pyridine compounds, and can also be used as a substituent for other organic synthesis reactions.
-In addition, it is also commonly used in the preparation of catalysts and the production of surfactants.
Preparation Method:
-3-Fluoro-4-methylpyriridine can be obtained by reacting pyridine with fluoromethane. The specific preparation method can adopt various methods, for example, the reaction of fluoromethane and pyridine under the catalysis of hydrofluoric acid, or the reaction using a fluorinating agent such as cesium fluoride.
Safety Information:
-3-Fluoro-4-methylpyriridine is irritating and corrosive and may cause irritation in contact with skin and eyes.
-Wear safety protective equipment such as gloves, glasses and protective clothing.
-Operate under closed ventilation and avoid inhalation of vapors and contact with skin.
-Avoid contact with oxidants and strong alkalis during storage, and avoid high temperature and fire sources.
-In case of contact or accident, please ask the hospital doctor for help immediately.
Nature:
-Appearance: colorless transparent liquid
-Melting point:-25°C
-Boiling point: 119-120°C
-Density: 1.13 g/mL(25°C)
-Solubility: Soluble in alcohol and ether solvents, insoluble in water.
Use:
-3-Fluoro-4-methylpyrridine is an important organic synthesis intermediate, commonly used in drug synthesis and pesticide synthesis. It can be used as a starting material for the synthesis of pyridine compounds, and can also be used as a substituent for other organic synthesis reactions.
-In addition, it is also commonly used in the preparation of catalysts and the production of surfactants.
Preparation Method:
-3-Fluoro-4-methylpyriridine can be obtained by reacting pyridine with fluoromethane. The specific preparation method can adopt various methods, for example, the reaction of fluoromethane and pyridine under the catalysis of hydrofluoric acid, or the reaction using a fluorinating agent such as cesium fluoride.
Safety Information:
-3-Fluoro-4-methylpyriridine is irritating and corrosive and may cause irritation in contact with skin and eyes.
-Wear safety protective equipment such as gloves, glasses and protective clothing.
-Operate under closed ventilation and avoid inhalation of vapors and contact with skin.
-Avoid contact with oxidants and strong alkalis during storage, and avoid high temperature and fire sources.
-In case of contact or accident, please ask the hospital doctor for help immediately.
Last Update：2024-04-09 20:52:54
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