3-AMINO-4-CHLORPYRIDINE
3-Amino-4-chloropyridine
CAS: 20511-15-3
Molecular Formula: C5H5ClN2
3-AMINO-4-CHLORPYRIDINE - Names and Identifiers
| Name | 3-Amino-4-chloropyridine |
| Synonyms | 4-CHLORO-3-PYRIDINAMINE 3-AMINO-4-CHLORPYRIDINE 4-chloropyridin-3-amine 4-Chloro-3-pyridinamine 3-Amino-4-chloropyridine 3-AMINO-4-CHLOROPYRIDINE 4-Chloro-3-aminopyridine 4-CHLORO-3-AMINO PYRIDINE 4-CHLORO-PYRIDIN-3-YLAMINE 3-Pyridinamine,4-chloro-(9CI) |
| CAS | 20511-15-3 |
| EINECS | 640-914-2 |
| InChI | InChI=1/C5H5ClN2/c6-4-1-2-8-3-5(4)7/h1-3H,7H2 |
| InChIKey | GTLFLMZOABSJSV-UHFFFAOYSA-N |
3-AMINO-4-CHLORPYRIDINE - Physico-chemical Properties
| Molecular Formula | C5H5ClN2 |
| Molar Mass | 128.56 |
| Density | 1.326±0.06 g/cm3(Predicted) |
| Melting Point | 58-63 °C |
| Boling Point | 247.6±20.0 °C(Predicted) |
| Flash Point | 103.5°C |
| Vapor Presure | 0.0254mmHg at 25°C |
| Appearance | Powder or Crystals |
| Color | White to yellow |
| BRN | 110187 |
| pKa | 3.77±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
| Refractive Index | 1.607 |
3-AMINO-4-CHLORPYRIDINE - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R41 - Risk of serious damage to eyes R37/38 - Irritating to respiratory system and skin. R25 - Toxic if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S39 - Wear eye / face protection. |
| UN IDs | 2811 |
| WGK Germany | 3 |
| HS Code | 29333990 |
| Hazard Class | IRRITANT |
| Packing Group | III |
3-AMINO-4-CHLORPYRIDINE - Introduction
3-Amino-4-chloropyridine is an organic compound with the chemical formula C5H5NCl. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
- 3-Amino-4-chloropyridine is a colorless to light yellow crystal with strong amine properties and easy to absorb moisture.
-It has medium solubility and can be dissolved in water and common organic solvents.
-The compound has a lower melting point and boiling point, 72-74 ° C and 206-208 ° C, respectively.
Use:
-3-amino-4-choropyridine is commonly used as a pharmaceutical intermediate, mainly for the synthesis of compounds in the field of medicine.
-It can also be used as a catalyst and a reagent for catalytic reactions in organic synthesis reactions.
Method:
- 3-Amino-4-chloropyridine can be obtained by reacting ammonia with 4-chloropyridine under alkaline conditions.
-In the laboratory, 3-Amino-4-chloropyridine can be prepared using hydrochlorination.
Safety Information:
- 3-Amino-4-chloropyridine is irritating and can cause irritation of the eyes, skin and respiratory tract. When in use, it is necessary to wear appropriate personal protective equipment.
-During the operation, care must be taken to avoid contact with skin and eyes, and to ensure that it is used in a well-ventilated area.
-During storage, the compound should be stored in a sealed container and avoid contact with oxidants and acidic substances.
-In the event of an accident or misuse, seek medical attention and obtain professional guidance immediately.
Please note that the use and handling of chemicals should follow safe operating procedures and comply with local laws and regulations.
Nature:
- 3-Amino-4-chloropyridine is a colorless to light yellow crystal with strong amine properties and easy to absorb moisture.
-It has medium solubility and can be dissolved in water and common organic solvents.
-The compound has a lower melting point and boiling point, 72-74 ° C and 206-208 ° C, respectively.
Use:
-3-amino-4-choropyridine is commonly used as a pharmaceutical intermediate, mainly for the synthesis of compounds in the field of medicine.
-It can also be used as a catalyst and a reagent for catalytic reactions in organic synthesis reactions.
Method:
- 3-Amino-4-chloropyridine can be obtained by reacting ammonia with 4-chloropyridine under alkaline conditions.
-In the laboratory, 3-Amino-4-chloropyridine can be prepared using hydrochlorination.
Safety Information:
- 3-Amino-4-chloropyridine is irritating and can cause irritation of the eyes, skin and respiratory tract. When in use, it is necessary to wear appropriate personal protective equipment.
-During the operation, care must be taken to avoid contact with skin and eyes, and to ensure that it is used in a well-ventilated area.
-During storage, the compound should be stored in a sealed container and avoid contact with oxidants and acidic substances.
-In the event of an accident or misuse, seek medical attention and obtain professional guidance immediately.
Please note that the use and handling of chemicals should follow safe operating procedures and comply with local laws and regulations.
Last Update：2024-04-09 15:17:54
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