3-AMINO-2-FLUOROBENZONITRILE
Benzonitrile, 3-amino-2-fluoro-
CAS: 873697-68-8
Molecular Formula: C7H5FN2
3-AMINO-2-FLUOROBENZONITRILE - Names and Identifiers
| Name | Benzonitrile, 3-amino-2-fluoro- |
| Synonyms | 3-Amino-2-Fluorobenzonitrile 3-amino-2-fluoroBenzonitrile 3-AMINO-2-FLUOROBENZONITRILE Benzonitrile, 3-amino-2-fluoro- |
| CAS | 873697-68-8 |
3-AMINO-2-FLUOROBENZONITRILE - Physico-chemical Properties
| Molecular Formula | C7H5FN2 |
| Molar Mass | 136.13 |
| Density | 1.25±0.1 g/cm3(Predicted) |
| Boling Point | 270.3±20.0 °C(Predicted) |
| pKa | 1.40±0.10(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
3-AMINO-2-FLUOROBENZONITRILE - Risk and Safety
| Hazard Class | IRRITANT |
3-AMINO-2-FLUOROBENZONITRILE - Introduction
Benzonitrile, 3-amino-2-fluoro-is an organic compound with the chemical formula C7H5FN2. It is a colorless liquid with a strong pungent odor at room temperature. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: colorless transparent liquid
-Molecular weight: 138.12g/mol
-Boiling point: 219-220 ℃
-Melting point:-17 ℃
-Density: 1.115g/cm³
-Solubility: Soluble in organic solvents such as alcohols, ethers and ketones
Use:
Benzonitrile, 3-amino-2-fluoro-has important application value in organic synthesis, and is often used as a pharmaceutical and pesticide intermediate. It can be used to synthesize a series of fluorine-containing organic compounds, such as drugs, pesticides, dyes and polymer materials.
Preparation Method:
Benzonitrile, 3-amino-2-fluoro-can be prepared by reacting 2-fluorobenzonitrile with ammonia. The reaction is generally carried out under an inert atmosphere, heated to reflux in an alkaline medium, and finally extracted with an organic solvent and purified by crystallization to obtain the target product.
Safety Information:
Benzonitrile, 3-amino-2-fluoro-is less toxic, but it is still necessary to pay attention to safe operation. When in use, wear appropriate protective equipment such as gloves, goggles and laboratory coats. Avoid contact with skin, eyes and inhalation of vapors. When handling this compound, make sure to work in a well-ventilated environment and follow correct waste disposal procedures.
Nature:
-Appearance: colorless transparent liquid
-Molecular weight: 138.12g/mol
-Boiling point: 219-220 ℃
-Melting point:-17 ℃
-Density: 1.115g/cm³
-Solubility: Soluble in organic solvents such as alcohols, ethers and ketones
Use:
Benzonitrile, 3-amino-2-fluoro-has important application value in organic synthesis, and is often used as a pharmaceutical and pesticide intermediate. It can be used to synthesize a series of fluorine-containing organic compounds, such as drugs, pesticides, dyes and polymer materials.
Preparation Method:
Benzonitrile, 3-amino-2-fluoro-can be prepared by reacting 2-fluorobenzonitrile with ammonia. The reaction is generally carried out under an inert atmosphere, heated to reflux in an alkaline medium, and finally extracted with an organic solvent and purified by crystallization to obtain the target product.
Safety Information:
Benzonitrile, 3-amino-2-fluoro-is less toxic, but it is still necessary to pay attention to safe operation. When in use, wear appropriate protective equipment such as gloves, goggles and laboratory coats. Avoid contact with skin, eyes and inhalation of vapors. When handling this compound, make sure to work in a well-ventilated environment and follow correct waste disposal procedures.
Last Update：2024-04-09 19:05:52
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View History
3-AMINO-2-FLUOROBENZONITRILE
Potassium thiocyanate
59459-49-3
pelagal eg
hexafluoro-phosphate(1-hydrogen
59997-51-2
硬脂酰胺
1689-82-3
9004-61-9
32760-80-8
Potassium thiocyanate
59459-49-3
pelagal eg
hexafluoro-phosphate(1-hydrogen
59997-51-2
硬脂酰胺
1689-82-3
9004-61-9
32760-80-8