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3-(4-broMophenyl)piperidin-2-one

3-(4-broMophenyl)piperidin-2-one

CAS: 769944-71-0

Molecular Formula: C11H12BrNO

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3-(4-broMophenyl)piperidin-2-one - Names and Identifiers

Name 3-(4-broMophenyl)piperidin-2-one
Synonyms 3-(4-bromophenyl)-2-Piperidinone
3-(4-broMophenyl)piperidin-2-one
2-Piperidinone, 3-(4-bromophenyl)-
CAS 769944-71-0

3-(4-broMophenyl)piperidin-2-one - Physico-chemical Properties

Molecular FormulaC11H12BrNO
Molar Mass254.12
Density1.416±0.06 g/cm3(Predicted)
Boling Point416.4±45.0 °C(Predicted)
pKa16.07±0.40(Predicted)
Storage ConditionSealed in dry,Room Temperature

3-(4-broMophenyl)piperidin-2-one - Reference Information

use 3-(4-bromophenyl) piperidin-2-one can be used as an intermediate in pharmaceutical synthesis.
application 3-(4-bromophenyl) piperidin-2-one can be used as an intermediate in pharmaceutical synthesis, such as preparation:




specific steps are as follows: 3-(4-bromophenyl) piperidin-2-one (7.6g,30mmol) was mixed in deuterated methanol (100g), heated to 40-45 ℃ under nitrogen protection, sodium methoxide (3.2g,60mmol) was added, and reacted at 40-45 ℃ for 16h. LCMS detection showed that the deuterated rate was 90%, and the reaction solution was cooled to 20-25 ℃, 100mL of ammonium chloride solution was added for quenching, extracted with ethyl acetate (100mL × 2), dried, concentrated to obtain crude product, and filtered with petroleum ether beating to obtain a white solid of 7.0g of 3-(4-bromophenyl)-3-deuterated piperidine -2-one with 92% yield. LCMS analysis showed that the deuteration rate was 92%, and nuclear magnetic resonance showed that the deuteration rate was 94%.
Last Update:2024-04-09 20:52:54
3-(4-broMophenyl)piperidin-2-one
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Email: 3623107365@qq.com
Mobile: 18916960931
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Shanghai Macklin Biochemical Co., Ltd
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CAS: 769944-71-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: 3-(4-broMophenyl)piperidin-2-one Visit Supplier Webpage Request for quotation
CAS: 769944-71-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: 3-(4-broMophenyl)piperidin-2-one Visit Supplier Webpage Request for quotation
CAS: 769944-71-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
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3-(4-broMophenyl)piperidin-2-one
Methyl 2-(3-oxetanylidene)acetate
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