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2556-73-2

N-Methylcaprolactam

CAS: 2556-73-2

Molecular Formula: C7H13NO

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2556-73-2 - Names and Identifiers

Name N-Methylcaprolactam
Synonyms 1-Methylcaprolactam
N-Methylcaprolactam
1-methylazepan-2-one
N-Methyl-e-caprolactam
epsilon-Caprolactam, N-methyl-
hexahydro-n-methyl-2h-azepin-2-on
hexahydro-1-methyl-2h-azepin-2-on
Hexahydro-1-methyl-2H-azepin-2-one
hexahydro-n-methyl-2h-azepin-2-one
2H-Azepin-2-one, hexahydro-N-methyl-
1-methyl-azepan-2-one(N-methyl-caprolactam)
CAS 2556-73-2
EINECS 219-874-1
InChI InChI=1/C7H13NO/c1-8-6-4-2-3-5-7(8)9/h2-6H2,1H3

2556-73-2 - Physico-chemical Properties

Molecular FormulaC7H13NO
Molar Mass127.18
Density0.991 g/mL at 25 °C (lit.)
Boling Point106-108 °C/6 mmHg (lit.)
Flash Point218°F
Water SolubilityFully miscible with water.
Solubility Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Sparingly)
Vapor Presure0.0252mmHg at 25°C
AppearanceOil
Specific Gravity0.991
ColorColourless
Merck14,5989
pKa-0.41±0.20(Predicted)
Storage ConditionKeep in dark place,Inert atmosphere,Room temperature
SensitiveHygroscopic
Refractive Indexn20/D 1.484(lit.)
Physical and Chemical PropertiesThe boiling point 106-108 ℃(0.8kPa), relative density 0.991, refractive index 1.4839, flash point 103 ℃.
UseUsed as a pharmaceutical Intermediate

2556-73-2 - Risk and Safety

Hazard SymbolsXn - Harmful
Harmful
Risk CodesR20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 - Irritating to eyes, respiratory system and skin.
R21/22 - Harmful in contact with skin and if swallowed.
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 - Wear suitable gloves and eye/face protection
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany3
RTECSCM4025000
HS Code29337900

2556-73-2 - Reference Information

NIST chemical information Information provided by: webbook.nist.gov (external link)
EPA chemical information Information provided by: ofmpub.epa.gov (external link)
use used as an intermediate and solvent for organic synthesis.
Used as a pharmaceutical intermediate
Production method It is obtained by the reaction of lactam and dimethyl sulfate. The caprolactam is dissolved in benzene, heated and refluxed, and dimethyl sulfate is added dropwise under stirring. After adding, reflux reaction for 16h, cooling, washing with 50% potassium carbonate solution, dividing the upper organic layer, drying with anhydrous calcium chloride overnight. After filtering out calcium chloride, benzene is distilled under normal pressure, and N-methyl caprolactam is collected by decompression distillation in drought. The yield was 68.8%.
Last Update:2024-04-10 22:29:15
2556-73-2
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