23612-57-9
2-Aminopyridine-3-methanol
CAS: 23612-57-9
Molecular Formula: C6H8N2O
23612-57-9 - Names and Identifiers
| Name | 2-Aminopyridine-3-methanol |
| Synonyms | 2-(Aminopyridine-3-yl) 2-Amino-3-pyridylmethanol 2-Amino-3-pyridinemethanol 2-Aminopyridine-3-methanol 2-AMINOPYRIDINE-3-METHANOL (2-AMINO-3-PYRIDINYL)METHANOL (2-Aminopyridin-3-yl)methanol 2-Amino-3-(hydroxymethyl)pyrid (2-Amino-pyridin-3-yl)-methanol (2-AMINO-PYRIDIN-3-YL)-METHANOL 3-(Hydroxymethyl)-2-pyridinamine 2-Amino-3-hydroxymethyl pyridine |
| CAS | 23612-57-9 |
| EINECS | 640-243-5 |
| InChI | InChI=1/C6H8N2O/c7-6-5(4-9)2-1-3-8-6/h1-3,9H,4H2,(H2,7,8) |
23612-57-9 - Physico-chemical Properties
| Molecular Formula | C6H8N2O |
| Molar Mass | 124.14 |
| Density | 1.257±0.06 g/cm3(Predicted) |
| Melting Point | 66-68°C |
| Boling Point | 320.7±27.0 °C(Predicted) |
| Flash Point | 147.7°C |
| Vapor Presure | 0.00013mmHg at 25°C |
| Appearance | Bright yellow crystal |
| Color | Pale-Yellow |
| pKa | 13.54±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Sensitive | Air Sensitive |
| Refractive Index | 1.627 |
| MDL | MFCD05663510 |
| Use | A pyridine derivative for proteomics research |
23612-57-9 - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37 - Wear suitable gloves. |
| WGK Germany | 3 |
| HS Code | 29333990 |
| Hazard Note | Irritant |
| Hazard Class | 6.1 |
23612-57-9 - Introduction
2-Aminopyridine-3-methanol is an organic compound with the chemical formula C6H8N2O. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline solid
-Melting point: 145-148 degrees Celsius
-Solubility: Slightly soluble in water, soluble in organic solvents such as methanol, ethanol and ether
-Chemical properties: It is alkaline and can be neutralized by acid to form salts. It can also be chemically modified by a substitution reaction.
Use:
-Drug intermediates: 2-Aminopyridine-3-methanol is an important drug intermediates, can be used for the synthesis of various drugs, such as anti-cancer drugs, antiviral drugs, anti-infective drugs.
-Organic synthesis: It can be used as a starting material or intermediate for the synthesis of other organic compounds and participate in a variety of organic synthesis reactions.
Method:
The preparation method of 2-Aminopyridine-3-methanol can be carried out by the following steps:
1. Synthesis of pyridine compounds: 2-aminopyridine was generated by reacting β-propyl amino alcohol with 2-cyanopyridine.
2. Reduction reaction: the synthesized 2-aminopyridine is reacted with hydrogen and reduced in the presence of an appropriate catalyst to generate 2-Aminopyridine-3-methanol.
Safety Information:
- 2-Aminopyridine-3-methanol is an organic compound and should be used with caution. Wear appropriate personal protective equipment such as gloves and safety glasses when handling or handling.
-Avoid contact with skin and inhalation. In the case of accidental contact, immediately flush the affected area with plenty of water and seek medical help.
-Follow proper laboratory procedures and safety measures when storing and handling.
-For more detailed safety information, please refer to the relevant chemical safety data sheets (MSDS) or obtain relevant information from reliable chemical information sources.
Nature:
-Appearance: White crystalline solid
-Melting point: 145-148 degrees Celsius
-Solubility: Slightly soluble in water, soluble in organic solvents such as methanol, ethanol and ether
-Chemical properties: It is alkaline and can be neutralized by acid to form salts. It can also be chemically modified by a substitution reaction.
Use:
-Drug intermediates: 2-Aminopyridine-3-methanol is an important drug intermediates, can be used for the synthesis of various drugs, such as anti-cancer drugs, antiviral drugs, anti-infective drugs.
-Organic synthesis: It can be used as a starting material or intermediate for the synthesis of other organic compounds and participate in a variety of organic synthesis reactions.
Method:
The preparation method of 2-Aminopyridine-3-methanol can be carried out by the following steps:
1. Synthesis of pyridine compounds: 2-aminopyridine was generated by reacting β-propyl amino alcohol with 2-cyanopyridine.
2. Reduction reaction: the synthesized 2-aminopyridine is reacted with hydrogen and reduced in the presence of an appropriate catalyst to generate 2-Aminopyridine-3-methanol.
Safety Information:
- 2-Aminopyridine-3-methanol is an organic compound and should be used with caution. Wear appropriate personal protective equipment such as gloves and safety glasses when handling or handling.
-Avoid contact with skin and inhalation. In the case of accidental contact, immediately flush the affected area with plenty of water and seek medical help.
-Follow proper laboratory procedures and safety measures when storing and handling.
-For more detailed safety information, please refer to the relevant chemical safety data sheets (MSDS) or obtain relevant information from reliable chemical information sources.
Last Update：2024-04-09 20:02:46
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View History
23612-57-9
59703-00-3
T10(carbohydrate)
2390-09-2
三氟乙酰丙酮
18240-93-2
Ethyl laurate
64-19-7
乙酰丙酮铅(II)
120077-69-2
59703-00-3
T10(carbohydrate)
2390-09-2
三氟乙酰丙酮
18240-93-2
Ethyl laurate
64-19-7
乙酰丙酮铅(II)
120077-69-2