228857-58-7

228857-58-7 - Names and Identifiers

Name	(R)-N-Boc-azetidine-2-carboxylic acid
Synonyms	(R)-1-Boc-azetidine-2-car... (R)-N-Boc-azetodome carboxylic Boc-D-Azetidine-2-carboxylic acid 1-Boc-D-azetidine-2-carboxylic acid Boc-(R)-azetidine-2-carboxylic acid (R)-N-Boc-azetidine carboxylic acid (R)-1-Boc-azetidine-2-carboxylic acid (R)-N-Boc-azetidine-2-carboxylic acid (R)-N-tert-Butoxycarbonylazetidine-2-carboxylic acid (R)-1-(tert-butoxycarbonyl)azetidine-2-carboxylic acid (R)-Azetidine-1,2-dicarboxylic acid 1-tert-butyl ester (2R)-1-(tert-butoxycarbonyl)azetidine-2-carboxylic acid
CAS	228857-58-7
InChI	InChI=1/C9H15NO4/c1-9(2,3)14-8(13)10-5-4-6(10)7(11)12/h6H,4-5H2,1-3H3,(H,11,12)/t6-/m1/s1

228857-58-7 - Physico-chemical Properties

Molecular Formula	C9H15NO4
Molar Mass	201.22
Density	1.246
Boling Point	321.0±35.0 °C(Predicted)
Flash Point	147.9°C
Vapor Presure	6.35E-05mmHg at 25°C
pKa	4.01±0.20(Predicted)
Storage Condition	2-8°C
Refractive Index	1.51

228857-58-7 - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
HS Code	29339900

228857-58-7 - Introduction

(R)-N-Boc-azetidine-2-carboxylic acid is an organic compound with the chemical formula C13H19NO4. It has the following properties:

1. Appearance: White or off-white crystalline solid.
2. Solubility: Soluble in some organic solvents such as methanol, ethanol, dimethyl sulfoxide and dichloromethane, slightly soluble in water.
3. Melting Point: about 110-115 degrees Celsius.

(R)-N-Boc-azetidine-2-carboxylic acid is mainly used in organic synthesis as a protecting group. It can be used to protect the nitrogen atoms of amino acids to prevent unwanted reactions during synthesis. It is widely used in the field of peptide synthesis and drug synthesis.

The method of preparing (R)-N-Boc-azetidine-2-carboxylic acid usually passes through the following steps:

1. React acridine dicarboxylic acid chloride (2-pyridinecarbonyl chloride) with (R)-carbonic acid (R)-carbonic acid) to produce acridine carboxylic acid dimethyl ester.
2. Carry out alkyd condensation reaction between 1-b-4-acridinol (Cr) and acridinecarboxylic acid dimethyl ester to generate (R)-N-Boc-azetidine-2-carboxylic acid.

safety precautions when using (R)-N-Boc-azetidine-2-carboxylic acid:

1. (R)-N-Boc-azetidine-2-carboxylic acid powder form may cause eye and skin irritation, should pay attention to protective measures such as wearing gloves and goggles.
2. Avoid inhaling dust or gas during operation. If inhalation occurs, please get enough oxygen from fresh air and seek medical help.
3. Avoid high temperature and fire sources during storage, and keep the container sealed and dry.

Before using (R)-N-Boc-azetidine-2-carboxylic acid, it is recommended to read its safety Technical Manual and operate in strict accordance with laboratory regulations and experimental operating procedures.

Last Update：2024-04-09 21:21:28

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