2266-48-0
Ethyl 2,2-difluoroacetoacetate
CAS: 2266-48-0
Molecular Formula: C6H8F2O3
2266-48-0 - Names and Identifiers
| Name | Ethyl 2,2-difluoroacetoacetate |
| Synonyms | Ethyl 2,2-difluoroacetoacetate ETHYL 2,2-DIFLUOROACETOACETATE Ethyl 2,2-difluoro-3-oxobutanoate ethyl 2,2-difluoro-3-oxobutanoate 2,2-difluoro-acetoaceticacidethylester 2,2-Difluoroacetoacetic acid ethyl ester 2,2-DIFLUORO-3-OXO-BUTYRIC ACID ETHYL ESTER Butanoic acid, 2,2-difluoro-3-oxo-, ethyl ester |
| CAS | 2266-48-0 |
| EINECS | 000-000-0 |
| InChI | InChI=1/C6H8F2O3/c1-3-11-5(10)6(7,8)4(2)9/h3H2,1-2H3 |
2266-48-0 - Physico-chemical Properties
| Molecular Formula | C6H8F2O3 |
| Molar Mass | 166.12 |
| Density | 1.2726 g/cm3(Temp: 0 °C) |
| Boling Point | 162°C |
| Flash Point | 162°C |
| Vapor Presure | 2.3mmHg at 25°C |
| BRN | 1769592 |
| Storage Condition | 2-8°C |
| Refractive Index | 1.4070 |
| MDL | MFCD00190633 |
2266-48-0 - Risk and Safety
| Risk Codes | R10 - Flammable R36/38 - Irritating to eyes and skin. |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| UN IDs | 1993 |
| Hazard Class | 3 |
| Packing Group | III |
2266-48-0 - Introduction
Ethyl 2,2-difluoroacetoacetate, also known as Ethyl 2,2-difluoroacetoacetate, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: colorless liquid
-Molecular formula: C6H7F2O3
-Molecular weight: 168.11g/mol
-Melting point:-56 ° C
-Boiling point: 108-110 ° C
-Density: 1.314g/cm3
-Soluble: Soluble in ethanol, ether and chlorinated hydrocarbons
Use:
- Ethyl 2,2-difluoroacetoacetate can be used as an important intermediate in organic synthesis, for the synthesis of drugs, pesticides and dyes and other compounds.
-It can also be used to prepare fluorinated compounds, halogenated ketones and other fluorine-containing compounds.
Method:
- Ethyl 2,2-difluoroacetoacetate is usually synthesized by the following steps:
1. Ethyl acetoacetate is reacted with difluoromethanyl chloride to generate chloroethyl 2,2-difluoroacetoacetate.
2. React chloroethyl 2,2-difluoroacetoacetate with ethanol to generate Ethyl 2,2-difluoroacetoacetate under the catalysis of alkali.
Safety Information:
- Ethyl 2,2-difluoroacetoacetate is irritating and should be avoided in contact with skin, eyes and mucous membranes.
-Wear appropriate personal protective equipment such as gloves, goggles and protective clothing during use or handling.
-Avoid fire and high temperature during storage and use to prevent it from burning and exploding.
-Waste disposal should comply with local laws and regulations to avoid environmental impact.
Nature:
-Appearance: colorless liquid
-Molecular formula: C6H7F2O3
-Molecular weight: 168.11g/mol
-Melting point:-56 ° C
-Boiling point: 108-110 ° C
-Density: 1.314g/cm3
-Soluble: Soluble in ethanol, ether and chlorinated hydrocarbons
Use:
- Ethyl 2,2-difluoroacetoacetate can be used as an important intermediate in organic synthesis, for the synthesis of drugs, pesticides and dyes and other compounds.
-It can also be used to prepare fluorinated compounds, halogenated ketones and other fluorine-containing compounds.
Method:
- Ethyl 2,2-difluoroacetoacetate is usually synthesized by the following steps:
1. Ethyl acetoacetate is reacted with difluoromethanyl chloride to generate chloroethyl 2,2-difluoroacetoacetate.
2. React chloroethyl 2,2-difluoroacetoacetate with ethanol to generate Ethyl 2,2-difluoroacetoacetate under the catalysis of alkali.
Safety Information:
- Ethyl 2,2-difluoroacetoacetate is irritating and should be avoided in contact with skin, eyes and mucous membranes.
-Wear appropriate personal protective equipment such as gloves, goggles and protective clothing during use or handling.
-Avoid fire and high temperature during storage and use to prevent it from burning and exploding.
-Waste disposal should comply with local laws and regulations to avoid environmental impact.
Last Update：2024-04-09 02:00:44
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View History
2266-48-0
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C.I.直接黄11
115375-60-5
2-Bromoethyl Ester
MethylaluminoxaneMAO
美达唑胺
氯化丁烯钯二聚体
可溶性还原棕5
1935075-34-5
紫菀酮