2221948-98-5
Bis-PEG21-NHS ester
CAS: 2221948-98-5
Molecular Formula: C54H96N2O29
2221948-98-5 - Names and Identifiers
| Name | Bis-PEG21-NHS ester |
| Synonyms | Bis-PEG21-NHS ester Bis-dPEG21-NHS ester |
| CAS | 2221948-98-5 |
2221948-98-5 - Physico-chemical Properties
| Molecular Formula | C54H96N2O29 |
| Molar Mass | 1237.34 |
| Storage Condition | 2-8°C，干燥，密封 |
| MDL | MFCD21363289 |
| In vitro study | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
2221948-98-5 - Reference Information
| biological activity | Bis-PEG21-NHS ester is a PROTAC connection bridge, belonging to PEG class and Alkyl/ether class. Bis-PEG21-NHS ester can be used to synthesize a series of PROTAC molecules. Bis-PEG21-NHS ester is a degradable (cleavable) ADC link bridge for the synthesis of antibody drug conjugates (ADCs). |
| target | PEGs Alkyl/ether Cleavable |
| in vitro study | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
Last Update：2024-04-09 01:59:58
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View History
2221948-98-5
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261762-98-5
乙烯基磷酸酯
沃尼妙林盐酸盐
R-Β-苯丙氨酸
2246335-51-1
1-碘代-4-硝基苯
十水四硼酸钠
Fmoc-D-Tle-OH
Guanidine Hydrochlorie