214353-17-0

214353-17-0 - Names and Identifiers

Name	2'-Amino-5'-chloro-2,2,2-trifluoroacetophenone
Synonyms	214353-17-0 2-TRIFLUOROACETYL-4-CHLORO ANILINE 2-Amino-5-chlorophenyl-2,2,2-trifluoroethanone 2'-Amino-5'-chloro-2,2,2-trifluoroacetophenone 2'-AMINO-5'-CHLORO-2,2,2-TRIFLUOROACETOPHENONE 2-AMINO-5-CHLORO-2',2',2'-TRIFLUOROACETOPHENONE 4-Chloro-2-trifluoroacetoaniline hydrochloride hydrate 1-(2-amino-5-chlorophenyl)-2,2,2-trifluoroethane-1,1-diol 4-chloro-2-(2,2,2-trifluoro-1,1-dihydroxyethyl)anilinium chloride 1-(2-Amino-5-chlorophenyl)-2,2,2-trifluoroethane-1,1-diol hydrochloride 1-(2-Amino-5-chlorophenyl)-2,2,2-trifluoro-1,1-ethanediol, hydrochloride 1,1-ETHANEDIOL, 1-(2-AMINO-5-CHLOROPHENYL)-2,2,2-TRIFLUORO-, HYDROCHLORIDE 4-Chloro-2-Trifluoroaceto Aniline Hydrochloride Hydrate (The Intermediate Of Efavirenz)
CAS	214353-17-0
EINECS	433-580-2
InChI	InChI=1/C8H7ClF3NO2/c9-4-1-2-6(13)5(3-4)7(14,15)8(10,11)12/h1-3,14-15H,13H2

214353-17-0 - Physico-chemical Properties

Molecular Formula	C8H5ClF3NO
Molar Mass	223.58
Density	1.624g/cm³
Boling Point	381.771°C at 760 mmHg
Flash Point	184.689°C
Vapor Presure	0mmHg at 25°C
Storage Condition	2-8°C(protect from light)
Refractive Index	1.559

214353-17-0 - Introduction

2 '-Amino-5'-chloro-2,2,2-trifluoroacetophenone is an organic compound with the chemical formula C8H6ClF3NO. Its properties are as follows:

1. Appearance: 2 '-Amino-5'-chloro-2,2,2-trifluoroacetophenone is colorless to light yellow crystal or powder.

2. Solubility: It can be dissolved in some organic solvents, such as ethanol, dimethyl ether and chloroform, but it is insoluble in water.

3. Use: 2 '-Amino-5'-chloro-2,2,2-trifluoroacetophenone is commonly used in organic synthesis, as a reagent or intermediate. It can be used to synthesize other organic compounds, such as dyes, pesticides and drugs.

4. Preparation method: A commonly used synthesis method is to prepare 2 '-Amino-5'-chloro-2,2,2-trifluoroacetophenone by chlorination of para-diaminophenone. A specific method includes the reaction of p-diaminobenzophenone with thionyl chloride and lithium aluminum thionyl chloride in an organic solvent.

5. Safety Information: 2 '-Amino-5'-chloro-2,2,2-trifluoroacetophenone should pay attention to safety during use. It may be irritating to the eyes, skin and respiratory system. Use appropriate protective equipment such as chemical goggles, gloves and masks. If you come into contact with this compound, rinse immediately with plenty of water and seek medical help. When storing and handling the compound, the appropriate safety procedures should be observed.

Last Update：2024-04-09 15:17:55