21190-89-6
ethyl 6-chloropyridine-2-carboxylate
CAS: 21190-89-6
Molecular Formula: C8H8ClNO2
21190-89-6 - Names and Identifiers
21190-89-6 - Physico-chemical Properties
| Molecular Formula | C8H8ClNO2 |
| Molar Mass | 185.61 |
| Density | 1.245 |
| Boling Point | 289℃ |
| Flash Point | 129℃ |
| Vapor Presure | 0.002mmHg at 25°C |
| Appearance | Crystalline |
| Color | Pale yellow |
| pKa | -0.89±0.10(Predicted) |
| Storage Condition | Room Temprature |
| Refractive Index | 1.525 |
21190-89-6 - Introduction
ethyl is an organic compound with the chemical formula C8H6ClNO2. It is a colorless liquid with a pungent odor. The following are other properties about the compound:
Nature:
-Density: approx. 1.28 g/mL
-Boiling point: About 250 ° C
-Melting point: about 29 ° C
-Solubility: Soluble in some organic solvents, such as ethanol, dichloromethane and ether
Use:
- ethyl L is widely used as an intermediate in organic synthesis and is used in the synthesis of drugs and pesticides.
-It can also be used as a solvent and catalyst in organic synthesis reactions.
Method: The preparation method of
ethyl L mainly includes the following steps:
1. React 6-chloropyridine with sodium cyanide to generate 6-chloropyridine -2-carbonitrile.
2. React 6-chloropyridine-2-carbonitrile with alcohol to generate 6-chloropyridine-2-carbonitrile alcohol.
3. Finally, 6-chloropyridine-2-nitrile alcohol is reacted with acid to generate ethyl L.
Safety Information:
ethyl L is irritating and may cause irritation to the skin, eyes and respiratory tract. Therefore, appropriate protective equipment such as gloves, safety glasses and respiratory protective equipment should be worn when the substance is used.
In addition, the compound is also flammable and should be kept away from open flames and high temperatures. Safe practices should be followed when storing and handling the substance.
Nature:
-Density: approx. 1.28 g/mL
-Boiling point: About 250 ° C
-Melting point: about 29 ° C
-Solubility: Soluble in some organic solvents, such as ethanol, dichloromethane and ether
Use:
- ethyl L is widely used as an intermediate in organic synthesis and is used in the synthesis of drugs and pesticides.
-It can also be used as a solvent and catalyst in organic synthesis reactions.
Method: The preparation method of
ethyl L mainly includes the following steps:
1. React 6-chloropyridine with sodium cyanide to generate 6-chloropyridine -2-carbonitrile.
2. React 6-chloropyridine-2-carbonitrile with alcohol to generate 6-chloropyridine-2-carbonitrile alcohol.
3. Finally, 6-chloropyridine-2-nitrile alcohol is reacted with acid to generate ethyl L.
Safety Information:
ethyl L is irritating and may cause irritation to the skin, eyes and respiratory tract. Therefore, appropriate protective equipment such as gloves, safety glasses and respiratory protective equipment should be worn when the substance is used.
In addition, the compound is also flammable and should be kept away from open flames and high temperatures. Safe practices should be followed when storing and handling the substance.
Last Update：2024-04-09 21:00:56
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View History
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