205927-03-3

205927-03-3 - Names and Identifiers

Name	(S)-(-)-5,5',6,6'-Tetramethyl-3,3'-di-t-butyl-1,1'-biphenyl-2,2'-diol
Synonyms	(S) BIPHEN H2 (R) BIPHEN H2 (R)-(+)-BIPHEN H2 RAC-3,3'-DI-T-BUTYL-5,5',6,6'-TETRAMETHYL-1,1'-BIPHENYL-2,2'-DIOL (S)-(-)-5,5',6,6'-Tetramethyl-3,3'-di-t-butyl-1,1'-biphenyl-2,2'-diol (R)-(+)-5,5',6,6'-TETRAMETHYL-3,3'-DI-T-BUTYL-1,1'-BIPHENYL-2,2'-DIOL RACEMIC-5,5',6,6'-TETRAMETHYL-3,3'-DI-T-BUTYL-1,1'-BIPHENYL-2,2'-DIOL (R)-(+)-5,5',6,6'-TETRAMETHYL-3,3'-DI-TERT-BUTYL-1,1'-BIPHENYL-2,2'-DIOL
CAS	205927-03-3

205927-03-3 - Physico-chemical Properties

Molecular Formula	C24H34O2
Molar Mass	354.53
Density	1.012±0.06 g/cm3(Predicted)
Melting Point	170-174°C
Boling Point	420.8±45.0 °C(Predicted)
Specific Rotation(α)	-78° (c 0.352, THF)
Appearance	Powder
Color	white
pKa	10.95±0.50(Predicted)
Storage Condition	2-8°C
MDL	MFCD01862439

205927-03-3 - Risk and Safety

Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3

205927-03-3 - Introduction

(S)-(-)5,5 ', 6,6'-tetramethyl-3, 3 '-di-tert-butyl-1, 1'-biphenyl-2, 2 '-diol is a chiral organic compound commonly abbreviated as (S)-(-)TMBB.

Nature:
(S)-(-)TMBB is a colorless crystalline solid, almost insoluble in water at room temperature, but soluble in organic solvents such as alcohols and ethers. It has high melting point and thermal stability, and can be used for reactions under high temperature conditions.

Use:
(S)-(-)TMBB is mainly used for asymmetric synthesis, and can be used as a chiral ligand to play the role of chiral recognition in metal-catalyzed reactions. It is often used in the fields of chiral catalytic reaction, chiral separation and chiral analysis in organic synthesis.

Preparation Method:
(S)-(-)TMBB has many preparation methods. The commonly used method is to react anthracene dione with diisopropyl lithium, and then obtain the target product through a series of reaction steps.

Safety Information:
(S)-(-)TMBB has not been reported to be significantly toxic or hazardous to humans. However, as a chemical substance, it is still necessary to pay attention to the correct operation method and personal protective measures to avoid contact with the skin and inhalation of its dust. Observe the relevant safety regulations during use and storage. If it is not properly handled, it may have a negative impact on the environment, and it should be handled and disposed of in accordance with the principles of environmental protection. In the course of use, if there is an accident, you should consult a doctor and seek help in a timely manner.

Last Update：2024-04-09 19:05:53