2-溴-3,3,3-三氟-1-丙醇
2-Bromo-3,3,3-trifluoro-1-propanol
CAS: 311-86-4
Molecular Formula: C3H4BrF3O
2-溴-3,3,3-三氟-1-丙醇 - Names and Identifiers
2-溴-3,3,3-三氟-1-丙醇 - Physico-chemical Properties
| Molecular Formula | C3H4BrF3O |
| Molar Mass | 192.96 |
| Density | 1.828±0.06 g/cm3(Predicted) |
| Boling Point | 126-127 °C |
| pKa | 13.30±0.10(Predicted) |
| Storage Condition | 2-8°C |
2-溴-3,3,3-三氟-1-丙醇 - Risk and Safety
| Hazard Symbols | F - Flammable |
2-溴-3,3,3-三氟-1-丙醇 - Introduction
2-Bromo-3,3,3-trifluoro-1-propanol is an organic compound with the chemical formula C3H5BrF3O. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless or light yellow liquid
-Melting point:-5 ℃
-Boiling point: 80-82 ℃
-Density: 1.90g/cm3
-Solubility: Soluble in water, alcohols and ethers, slightly soluble in aromatics and alkanes
Use:
- 2-Bromo-3,3,3-trifluoro-1-propanol can be used as a reagent in the synthesis of drugs.
-It can also be used as a catalyst and solvent for organic synthesis reactions.
Method:
The preparation of -2-Bromo-3,3,3-trifluoro-1-propanol is generally carried out by the following steps:
1. Oxidation of propylene to generate 3,3,3-trifluoropropionaldehyde.
2. Reacting 3,3, 3-trifluoropropionaldehyde with hydrobromic acid to give 2-Bromo-3, 3,3-trifluororo-1-propanol.
Safety Information:
- 2-Bromo-3,3,3-trifluoro-1-propanol is an irritating compound that may be harmful to the eyes, skin and respiratory system. Appropriate protective measures such as gloves, goggles and masks should be worn.
-It should be kept away from fire sources, heat sources and oxidants, and stored in a cool, dry place.
-When using or storing, please follow the relevant safety procedures and dispose of waste as needed.
Nature:
-Appearance: Colorless or light yellow liquid
-Melting point:-5 ℃
-Boiling point: 80-82 ℃
-Density: 1.90g/cm3
-Solubility: Soluble in water, alcohols and ethers, slightly soluble in aromatics and alkanes
Use:
- 2-Bromo-3,3,3-trifluoro-1-propanol can be used as a reagent in the synthesis of drugs.
-It can also be used as a catalyst and solvent for organic synthesis reactions.
Method:
The preparation of -2-Bromo-3,3,3-trifluoro-1-propanol is generally carried out by the following steps:
1. Oxidation of propylene to generate 3,3,3-trifluoropropionaldehyde.
2. Reacting 3,3, 3-trifluoropropionaldehyde with hydrobromic acid to give 2-Bromo-3, 3,3-trifluororo-1-propanol.
Safety Information:
- 2-Bromo-3,3,3-trifluoro-1-propanol is an irritating compound that may be harmful to the eyes, skin and respiratory system. Appropriate protective measures such as gloves, goggles and masks should be worn.
-It should be kept away from fire sources, heat sources and oxidants, and stored in a cool, dry place.
-When using or storing, please follow the relevant safety procedures and dispose of waste as needed.
Last Update：2024-04-09 02:00:45
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