2-hydroxy-2-phenylacetophenone
Benzoin
CAS: 119-53-9;579-44-2
Molecular Formula: C14H12O2
2-hydroxy-2-phenylacetophenone - Names and Identifiers
| Name | Benzoin |
| Synonyms | Benzoin DL-benzoin benzoylphenylcarbinol bitter almond oil camphor hydroxy-2-phenyl acetophenone 2-Hydroxy-1,2-diphenylethanone 2-hydroxy-2-phenylacetophenone Alpha-hydroxybenzyl phenyl ketone Alpha-hydroxy-a-phenylacetophenone |
| CAS | 119-53-9 579-44-2 |
| EINECS | 209-441-5 |
| InChI | InChI=1/C14H12O2/c15-13(11-7-3-1-4-8-11)14(16)12-9-5-2-6-10-12/h1-10,13,15H |
2-hydroxy-2-phenylacetophenone - Physico-chemical Properties
| Molecular Formula | C14H12O2 |
| Molar Mass | 212.24 |
| Density | 1.179g/cm3 |
| Melting Point | 134-136℃ |
| Boling Point | 343°C at 760 mmHg |
| Flash Point | 154.8°C |
| Solubility | Soluble in hot water, pyridine, boiling ethanol and acetone, slightly soluble in cold water and ether, insoluble in cold water |
| Vapor Presure | 2.78E-05mmHg at 25°C |
| Appearance | Pale yellow powder |
| Storage Condition | 2-8℃ |
| Sensitive | Easily absorbing moisture |
| Refractive Index | 1.609 |
| MDL | MFCD00004496 |
| Physical and Chemical Properties | White or light yellow crystal solubility insoluble in cold water, slightly soluble in hot water and ether, soluble in ethanol other properties can be reduced by Ferlin's solution, and concentrated sulfuric acid to form bibenzoyl. The reaction with sodium amalgam in ethanol produces hydrogenated benzoyl. It reacts with hydroiodic acid at 250 °c to form bifonyl. |
| Use | Used as pharmaceutical intermediates, can also be used in the production of dyes and photosensitive resin photosensitizer, gravure ink, photocurable coatings; Is to eliminate the bubbles in the molten powder coating liquid, that is, to eliminate the formation of film pinhole defects of the main factors; For the fluorescence reaction test of zinc, organic synthesis, as a standard and preservatives, etc; It is an ideal additive for the removal of pinholes in powder coatings in the production of powder coatings |
2-hydroxy-2-phenylacetophenone - Risk and Safety
| Safety Description | S24/25 - Avoid contact with skin and eyes. |
2-hydroxy-2-phenylacetophenone - Nature
Open Data Verified Data
white or light yellow prism crystals. Melting point 133 °c. Boiling point 344 °c. Insoluble in cold water, slightly soluble in hot water and ether, soluble in ethanol. Ferlin's solution can be reduced, and concentrated sulfuric acid to form bifonyl. The reaction with sodium amalgam in ethanol produces hydrogenated benzoyl. It reacts with hydroiodic acid at 250 °c to form bifonyl.
Last Update：2025-06-10 22:55:16
2-hydroxy-2-phenylacetophenone - Preparation Method
Open Data Verified Data
prepared by co-heating benzaldehyde with a small amount of potassium cyanide. Benzaldehyde and ethanol were added into the reaction flask, and then a small amount of potassium cyanide aqueous solution was added, heated and refluxed in a water bath for 1H, allowed to stand, filtered to obtain a crude product, and recrystallized with ethanol to obtain a finished product.
Last Update：2022-01-01 10:42:48
2-hydroxy-2-phenylacetophenone - Application
Open Data Verified Data
This product is a raw material for organic synthesis, used for the preparation of biphenylformyl, etc.; The pharmaceutical industry is used for the preparation of phenytoin sodium.
Last Update：2025-08-19 16:24:40
2-hydroxy-2-phenylacetophenone - Safety
Open Data Verified Data
- Thermal decomposition or combustion gives off a highly toxic gas that is irritating. Inhalation, ingestion and skin contact are harmful. Wear glasses, protective clothing and protective gloves.
- composite woven bag or carton, 25kg per barrel. Store in a cool, dry place, container sealed. Stay away from strong oxidants.
Last Update：2025-06-10 22:55:16
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