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2-bromo-4-(trifluoromethyl)pyridine

2-bromo-4-(trifluoromethyl)pyridine

CAS: 175205-81-9

Molecular Formula: C6H3BrF3N

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2-bromo-4-(trifluoromethyl)pyridine - Names and Identifiers

Name 2-bromo-4-(trifluoromethyl)pyridine
Synonyms 2-Bromo-4-trifluormethylpyridine
2-Bromo-4-Trifluoromethylpyridine
2-BROMO-4-(TRIFLUOROMETHYL)PYRIDINE
2-bromo-4-(trifluoromethyl)pyridine
Pyridine, 2-broMo-4-(trifluoroMethyl)-
2-Bromo-alpha,alpha,alpha-trifluoro-4-picoline
CAS 175205-81-9
EINECS 672-057-5
InChI InChI=1/C6H3BrF3N/c7-5-4(6(8,9)10)2-1-3-11-5/h1-3H
InChIKey WZVHLUMAQLUNTJ-UHFFFAOYSA-N

2-bromo-4-(trifluoromethyl)pyridine - Physico-chemical Properties

Molecular FormulaC6H3BrF3N
Molar Mass225.99
Density1.827 g/mL at 25 °C
Melting Point-21--20 °C
Boling Point84-85 °C/14 mmHg
Flash Point164°F
Vapor Presure0.622mmHg at 25°C
Appearanceclear liquid
ColorColorless to Light yellow to Light orange
pKa-1.57±0.10(Predicted)
Storage ConditionKeep in dark place,Sealed in dry,Room Temperature
Refractive Indexn20/D 1.478
MDLMFCD00153085
UseIn the C- 3, a regioselective deprotonation reaction occurs with LDA, which is subsequently captured by carbon dioxide to generate the corresponding nicotinic acid.

2-bromo-4-(trifluoromethyl)pyridine - Risk and Safety

Risk CodesR25 - Toxic if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin.
R37/38 - Irritating to respiratory system and skin.
R36 - Irritating to the eyes
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37 - Wear suitable protective clothing and gloves.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S37 - Wear suitable gloves.
UN IDsUN 2810 6.1/PG 3
WGK Germany3
Hazard NoteToxic/Irritant
Hazard ClassIRRITANT
Packing GroupⅢ

2-bromo-4-(trifluoromethyl)pyridine - Reference Information

Use Regioselective deprotonation reaction occurs with LDA in C- 3, and then is captured by carbon dioxide to generate the corresponding nicotinic acid.
Last Update:2024-04-09 21:01:54
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View History
2-bromo-4-(trifluoromethyl)pyridine
川芎嗪
2-(4,5-二甲氧基-2-硝基苯基)乙腈
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