2-TrifluoroMethyl-4-broMoquinoline
4-bromo-2-(trifluoromethyl)quinoline
CAS: 18706-25-7
Molecular Formula: C10H5BrF3N
2-TrifluoroMethyl-4-broMoquinoline - Names and Identifiers
| Name | 4-bromo-2-(trifluoromethyl)quinoline |
| Synonyms | 2-TrifluoroMethyl-4-broMoquinoline 4-bromo-2-(trifluoromethyl)quinoline Quinoline, 4-bromo-2-(trifluoromethyl)- quinoline, 4-bromo-2-(trifluoromethyl)- 4-Bromo-2-(trifluoromethyl)-1-azanaphthalene |
| CAS | 18706-25-7 |
| InChI | InChI=1/C10H5BrF3N/c11-7-5-9(10(12,13)14)15-8-4-2-1-3-6(7)8/h1-5H |
2-TrifluoroMethyl-4-broMoquinoline - Physico-chemical Properties
| Molecular Formula | C10H5BrF3N |
| Molar Mass | 276.05 |
| Density | 1.658 |
| Boling Point | 268.9±35.0 °C(Predicted) |
| Flash Point | 116.445°C |
| Vapor Presure | 0.012mmHg at 25°C |
| pKa | -1.38±0.50(Predicted) |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.573 |
2-TrifluoroMethyl-4-broMoquinoline - Introduction
4-bromo-2-(trifluoromethyl)quinoline, also known as quartz, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 4-bromo-2-(trifluoromethyl)quinoline is a colorless crystal or light yellow solid.
-Solubility: It is soluble in common organic solvents, such as ethanol, ether and dichloromethane.
-Melting point: Its melting point is about 80-85 degrees Celsius.
-Boiling point: Its boiling point is about 296 degrees Celsius.
-Chemical properties: The compound is stable to heat and light, and is relatively stable under acidic and alkaline conditions. It can be used as a reagent in the synthesis of aromatic compounds.
Use:
-Chemical synthesis: 4-bromo-2-(trifluoromethyl)quinoline can be used as an important intermediate in organic synthesis. It can be used to synthesize pharmaceutically active or other organic compounds.
-Drug development: It has important application potential in the field of medicine and can be used to develop new drugs or improve existing drugs.
-Pesticide: This compound can also be used for the development and preparation of pesticides.
Method:
-Generally, the preparation method of 4-bromo-2-(trifluoromethyl)quinoline is obtained by acylation of 3-bromobenzoylformate with fluoroacetic acid. The reaction is carried out under appropriate conditions, and usually a solvent and a catalyst are used to promote the reaction.
Safety Information:
-Due to the lack of sufficient toxicity assessment data, the information on toxicity and safety is not complete.
-During handling and use, follow appropriate laboratory practices and take necessary personal protective measures, such as wearing gloves, safety glasses and protective clothing.
-During storage, store in a sealed container to avoid contact with oxygen, fire or combustibles.
Nature:
-Appearance: 4-bromo-2-(trifluoromethyl)quinoline is a colorless crystal or light yellow solid.
-Solubility: It is soluble in common organic solvents, such as ethanol, ether and dichloromethane.
-Melting point: Its melting point is about 80-85 degrees Celsius.
-Boiling point: Its boiling point is about 296 degrees Celsius.
-Chemical properties: The compound is stable to heat and light, and is relatively stable under acidic and alkaline conditions. It can be used as a reagent in the synthesis of aromatic compounds.
Use:
-Chemical synthesis: 4-bromo-2-(trifluoromethyl)quinoline can be used as an important intermediate in organic synthesis. It can be used to synthesize pharmaceutically active or other organic compounds.
-Drug development: It has important application potential in the field of medicine and can be used to develop new drugs or improve existing drugs.
-Pesticide: This compound can also be used for the development and preparation of pesticides.
Method:
-Generally, the preparation method of 4-bromo-2-(trifluoromethyl)quinoline is obtained by acylation of 3-bromobenzoylformate with fluoroacetic acid. The reaction is carried out under appropriate conditions, and usually a solvent and a catalyst are used to promote the reaction.
Safety Information:
-Due to the lack of sufficient toxicity assessment data, the information on toxicity and safety is not complete.
-During handling and use, follow appropriate laboratory practices and take necessary personal protective measures, such as wearing gloves, safety glasses and protective clothing.
-During storage, store in a sealed container to avoid contact with oxygen, fire or combustibles.
Last Update：2024-04-09 21:04:16
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View History
2-TrifluoroMethyl-4-broMoquinoline
二乙烯三胺五甲基膦酸钠 DTPMPNAX
4-amino-m-creso
N-(2-羧苯基)甘氨酸
氟铬酸吡啶酯(免费送的样品)
2-Chloropyridine-3-carbonyl chloride
1-苄基-3-氨基氮杂环丁烷
六氟磷酸三苯基碳烯正离子
F luoroMethyl-Phosphonic acid diethyl ester
3-(1-羟乙基)苯基硼酸
二乙烯三胺五甲基膦酸钠 DTPMPNAX
4-amino-m-creso
N-(2-羧苯基)甘氨酸
氟铬酸吡啶酯(免费送的样品)
2-Chloropyridine-3-carbonyl chloride
1-苄基-3-氨基氮杂环丁烷
六氟磷酸三苯基碳烯正离子
F luoroMethyl-Phosphonic acid diethyl ester
3-(1-羟乙基)苯基硼酸