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2-Phenoxyethylamine

2-Phenoxyethylamine

CAS: 1758-46-9

Molecular Formula: C8H11NO

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2-Phenoxyethylamine - Names and Identifiers

Name 2-Phenoxyethylamine
Synonyms BUTTPARK 9757-78
2-phenoxyethylamino
2-PHENOXYETHYLAMINE
2-Phenoxyethylamine
2-Phenoxyethanamine
2-PHENOXYLETHYLAMINE
2-phenoxyethylammonium
alpha-phenoxy-beta-aminoethane
CAS 1758-46-9
EINECS 217-153-6
InChI InChI=1/C8H11NO/c9-6-7-10-8-4-2-1-3-5-8/h1-5H,6-7,9H2/p+1

2-Phenoxyethylamine - Physico-chemical Properties

Molecular FormulaC8H11NO
Molar Mass137.18
Density1.048 g/mL at 25 °C (lit.)
Boling Point101-103 °C/4 mmHg (lit.)
Flash Point225°F
Vapor Presure0.0665mmHg at 25°C
Specific Gravity1.048
BRN774671
pKa8.18±0.10(Predicted)
Storage Conditionunder inert gas (nitrogen or Argon) at 2–8 °C
StabilityStable. Combustible. Incompatible with strong oxidizing agents.
SensitiveAir Sensitive
Refractive Indexn20/D 1.536(lit.)
UseFor the synthesis of Nefazodone and other raw materials

2-Phenoxyethylamine - Risk and Safety

Hazard SymbolsC - Corrosive
Corrosive
Risk Codes34 - Causes burns
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDsUN 2735 8/PG 3
WGK Germany3
RTECSKR9500000
HS Code29221990
Hazard Class8
Packing GroupIII

2-Phenoxyethylamine - Reference Information

use 2-phenoxyethylamine is an important intermediate in the production of nefazodone. Nefazodone, an antidepressant for benpiperazine. The structure is related to trazodone. It can block the reuptake of 5-HT by presynaptic neurons and is an antagonist of postsynaptic 5-HT2 receptors. Unlike trazodone, 2-phenoxyethylamine inhibits the reuptake of norepinephrine. 2-Phenoxyethylamine can also block α1-receptors, but has no obvious effect on dopamine receptors. There was no significant antimuscarinic effect compared to other tricyclic antidepressants.
for the synthesis of naphthalazodone and other raw materials
Last Update:2024-04-09 21:01:54
2-Phenoxyethylamine
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View History
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