| Name | ARN-2966 |
| Synonyms | 2-PMAP ARN-2966 ARN 2966 102212-26-0 ARN2966(2-PMAP) 2-((pyridin-2-ylmethyl)amino)phenol Phenol, 2-[(2-pyridinylmethyl)amino]- |
| CAS | 102212-26-0 |
| Molecular Formula | C12H12N2O |
| Molar Mass | 200.24 |
| Density | 1.241±0.06 g/cm3(Predicted) |
| Melting Point | 130 °C(Solv: chloroform (67-66-3); hexane (110-54-3)) |
| Boling Point | 354.4±27.0 °C(Predicted) |
| Solubility | DMSO: ≥ 43.4 mg/mL |
| pKa | 10.22±0.35(Predicted) |
| Storage Condition | -20℃ |
| Physical and Chemical Properties | Bioactive ARN2966 is an efficient post-transcriptional regulator of APP expression, which reduces the expression of APP but reduces the amount of Aβ. |
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 4.994 ml | 24.97 ml | 49.941 ml |
| 5 mM | 0.999 ml | 4.994 ml | 9.988 ml |
| 10 mM | 0.499 ml | 2.497 ml | 4.994 ml |
| 5 mM | 0.1 ml | 0.499 ml | 0.999 ml |
| melting point | 130 °C(Solv: chloroform (67-66-3); hexane (110-54-3)) |
| boiling point | 354.4±27.0 °C(Predicted) |
| density | 1.241±0.06 g/cm3(Predicted) |
| acidity coefficient (pKa) | 10.22±0.35(Predicted) |
| biological activity | ARN2966 is an efficient post-transcriptional regulator for APP expression, reducing APP expression and thus reducing the amount of Aβ. |
| biological activity | ARN2966 is an efficient, post-transcriptional regulator of APP expression, reducing APP expression but reducing the amount of Aβ. |