2-Methyl-7-bromoquinoline
7-Bromo-2-methylquinoline
CAS: 4965-34-8
Molecular Formula: C10H8BrN
2-Methyl-7-bromoquinoline - Names and Identifiers
| Name | 7-Bromo-2-methylquinoline |
| Synonyms | 2-Methyl-7-bromoquinoline 7-BROMO-2-METHYLQUINOLINE 2-Methyl-7-broMoquinoline 7-Bromo-2-methylquinoline Quinoline, 7-bromo-2-methyl- quinoline, 7-bromo-2-methyl- |
| CAS | 4965-34-8 |
| InChI | InChI=1/C10H8BrN/c1-7-2-3-8-4-5-9(11)6-10(8)12-7/h2-6H,1H3 |
2-Methyl-7-bromoquinoline - Physico-chemical Properties
| Molecular Formula | C10H8BrN |
| Molar Mass | 222.08 |
| Density | 1.488±0.06 g/cm3(Predicted) |
| Melting Point | 77-79 °C |
| Boling Point | 299.7±20.0 °C(Predicted) |
| Flash Point | 135.042°C |
| Vapor Presure | 0.002mmHg at 25°C |
| pKa | 4.25±0.50(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.654 |
2-Methyl-7-bromoquinoline - Risk and Safety
| Risk Codes | 41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. |
2-Methyl-7-bromoquinoline - Introduction
7-Bromo-2-methylquinoline is an organic compound with the chemical formula C10H8BrN. The following is a detailed description of its nature, use, formulation and safety information:
Nature:
-Appearance: Pale yellow to yellow crystalline solid.
-Melting point: about 80-82 degrees Celsius.
-Boiling point: about 357 degrees Celsius.
-Density: Approximately 1.52 g/mL.
-Solubility: Soluble in chloroform, alcohol, ether and other organic solvents, slightly soluble in water.
Use:
7-Bromo-2-methylquinoline has a wide range of applications in chemical research and organic synthesis:
-It is an important intermediate that can be used to prepare other compounds containing quinoline structure.
-In the field of drug research, it can be used to synthesize biologically active compounds, such as anti-tumor drugs.
-In pesticide research, it can also be used as a raw material and intermediate for pesticides.
Preparation Method:
The preparation of 7-Bromo-2-methylquinoline usually uses the following steps:
1.2-methyl quinoline and excess sodium bromide are reacted in sodium hydroxide or alkaline solution to generate brominated products.
2. Use an organic solvent for neutralization and extraction to separate the target product.
3. Finally, the product was purified by crystallization, filtration and drying.
Safety Information:
- 7-Bromo-2-methylquinoline has no obvious harm to human body and environment under normal conditions.
-As a chemical, use should strictly follow the safety procedures, such as wearing appropriate protective equipment, maintaining a well-ventilated working environment, etc.
-It should be stored in a dry, cool place, away from fire and combustibles.
-When handling or transporting, avoid contact with strong oxidants and strong acids, and be careful to prevent dust.
Please note that this is only a general introduction to 7-Bromo-2-methylquinoline, and the specific use should follow the laboratory's operating instructions and relevant regulations.
Nature:
-Appearance: Pale yellow to yellow crystalline solid.
-Melting point: about 80-82 degrees Celsius.
-Boiling point: about 357 degrees Celsius.
-Density: Approximately 1.52 g/mL.
-Solubility: Soluble in chloroform, alcohol, ether and other organic solvents, slightly soluble in water.
Use:
7-Bromo-2-methylquinoline has a wide range of applications in chemical research and organic synthesis:
-It is an important intermediate that can be used to prepare other compounds containing quinoline structure.
-In the field of drug research, it can be used to synthesize biologically active compounds, such as anti-tumor drugs.
-In pesticide research, it can also be used as a raw material and intermediate for pesticides.
Preparation Method:
The preparation of 7-Bromo-2-methylquinoline usually uses the following steps:
1.2-methyl quinoline and excess sodium bromide are reacted in sodium hydroxide or alkaline solution to generate brominated products.
2. Use an organic solvent for neutralization and extraction to separate the target product.
3. Finally, the product was purified by crystallization, filtration and drying.
Safety Information:
- 7-Bromo-2-methylquinoline has no obvious harm to human body and environment under normal conditions.
-As a chemical, use should strictly follow the safety procedures, such as wearing appropriate protective equipment, maintaining a well-ventilated working environment, etc.
-It should be stored in a dry, cool place, away from fire and combustibles.
-When handling or transporting, avoid contact with strong oxidants and strong acids, and be careful to prevent dust.
Please note that this is only a general introduction to 7-Bromo-2-methylquinoline, and the specific use should follow the laboratory's operating instructions and relevant regulations.
Last Update：2024-04-09 15:17:58
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View History
2-Methyl-7-bromoquinoline
Trimethylsulfoxonium bromide
Trimethylsilyl methanesulphonate
Phenylphosphorus thiodichloride
151157-59-4
Trimethylsulfoxonium bromide
Trimethylsilyl methanesulphonate
Phenylphosphorus thiodichloride
151157-59-4