2-Chloro-5-cyano-4-iodopyridine
6-chloro-4-iodopyridine-3-carbonitrile
CAS: 1061357-83-2
Molecular Formula: C6H2ClIN2
2-Chloro-5-cyano-4-iodopyridine - Names and Identifiers
2-Chloro-5-cyano-4-iodopyridine - Physico-chemical Properties
| Molecular Formula | C6H2ClIN2 |
| Molar Mass | 264.45 |
| Density | 2.13±0.1 g/cm3(Predicted) |
| Boling Point | 329.3±42.0 °C(Predicted) |
| pKa | -3.73±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
2-Chloro-5-cyano-4-iodopyridine - Introduction
6-Chloro-4-iodo-3-nitrilopyridine (CIP) is an organic compound with the chemical formula C9H4ClIN2. The following is an introduction to some of the properties, uses, methods and safety information of CIP:
Nature:
-Appearance: colorless crystal or white powder
-Solubility: Soluble in organic solvents such as ethanol, dimethylformamide and dimethyl sulfoxide
-Melting point: about 152-153°C
-Stability: CIP is a stable compound, which is not easy to decompose under conventional experimental conditions
Use:
-Active intermediate: CIP can be used as an active intermediate in organic synthesis for the synthesis of organic compounds, such as pyridine compounds, iodine compounds, etc.
Preparation Method:
CIP can be synthesized by the following steps:
1. Add pyronitrosamine in iodobenzene and react to synthesize 3-chloro-4-iodopyridine
2. Cyanation of 3-chloro-4-iodopyridine to obtain 6-chloro-4-iodo-3-carbonylpyridine
Safety Information:
- CIP is an organic compound with certain toxicity and requires attention to safe operation.
-in the use of CIP, should follow the laboratory safety procedures, wear protective glasses, gloves, clothing and other personal protective equipment.
-Avoid contact with skin and eyes, and avoid inhaling its dust or vapor.
-Pay attention to fire prevention and static electricity accumulation during storage and handling, and avoid contact with oxidants.
Nature:
-Appearance: colorless crystal or white powder
-Solubility: Soluble in organic solvents such as ethanol, dimethylformamide and dimethyl sulfoxide
-Melting point: about 152-153°C
-Stability: CIP is a stable compound, which is not easy to decompose under conventional experimental conditions
Use:
-Active intermediate: CIP can be used as an active intermediate in organic synthesis for the synthesis of organic compounds, such as pyridine compounds, iodine compounds, etc.
Preparation Method:
CIP can be synthesized by the following steps:
1. Add pyronitrosamine in iodobenzene and react to synthesize 3-chloro-4-iodopyridine
2. Cyanation of 3-chloro-4-iodopyridine to obtain 6-chloro-4-iodo-3-carbonylpyridine
Safety Information:
- CIP is an organic compound with certain toxicity and requires attention to safe operation.
-in the use of CIP, should follow the laboratory safety procedures, wear protective glasses, gloves, clothing and other personal protective equipment.
-Avoid contact with skin and eyes, and avoid inhaling its dust or vapor.
-Pay attention to fire prevention and static electricity accumulation during storage and handling, and avoid contact with oxidants.
Last Update：2024-04-10 22:29:15
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View History
2-Chloro-5-cyano-4-iodopyridine
5-Ethoxycarbonyl-2-thienylzinc bromide solution 0.5 in THF
2-(2-氟-4-(三氟甲基)苯基)环丙烷-1-羧酸
N-acetyl-D-norleucine
prop-2-en-1-yl 3-oxobutanoate
5-Ethoxycarbonyl-2-thienylzinc bromide solution 0.5 in THF
2-(2-氟-4-(三氟甲基)苯基)环丙烷-1-羧酸
N-acetyl-D-norleucine
prop-2-en-1-yl 3-oxobutanoate