2-Bromo-5-Fluoro-3-Picoline
2-bromo-5-fluoro-3-methyl-pyridine
CAS: 38186-85-5
Molecular Formula: C6H5BrFN
2-Bromo-5-Fluoro-3-Picoline - Names and Identifiers
| Name | 2-bromo-5-fluoro-3-methyl-pyridine |
| Synonyms | LogP 2-Bromo-5-fluoro-3-picoline 2-Bromo-5-Fluoro-3-Picoline 2-bromo-5-fluoro-3-methylpyridine 2-bromo-5-fluoro-3-methyl-pyridine Pyridine, 2-bromo-5-fluoro-3-methyl- |
| CAS | 38186-85-5 |
| InChI | InChI=1/C6H5BrFN/c1-4-2-5(8)3-9-6(4)7/h2-3H,1H3 |
2-Bromo-5-Fluoro-3-Picoline - Physico-chemical Properties
| Molecular Formula | C6H5BrFN |
| Molar Mass | 190.01 |
| Density | 1.598 |
| Melting Point | 97-101℃ |
| Boling Point | 200.2±35.0 °C(Predicted) |
| Flash Point | 96℃ |
| Vapor Presure | 0.464mmHg at 25°C |
| pKa | -1.34±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.540 |
| MDL | MFCD09835355 |
2-Bromo-5-Fluoro-3-Picoline - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. |
| WGK Germany | 3 |
2-Bromo-5-Fluoro-3-Picoline - Introduction
It is an organic compound with the formula C6H5BrFN. It is a white solid with a special smell.
This compound is often used as an intermediate in organic synthesis to construct compounds with specific biological activities. It can also be used for research and development in the field of pesticides and pharmaceuticals.
The preparation is usually prepared by reacting 2,5-difluoro-N-picoline with ammonium bromide. The specific preparation method is as follows:
1. Dissolve 2,5-difluoro-N-picoline in an appropriate amount of solvent.
2. Ammonium bromide was added to the above solution.
3. Stir the reaction at an appropriate temperature for a period of time.
4. Filter the product and dry it to get it.
Regarding safety, it should be handled with caution. It may irritate the eyes, skin and respiratory system. During use, appropriate personal protective equipment should be worn to avoid direct contact. At the same time, it should be operated in a well-ventilated place to avoid inhaling its vapor or dust. In case of accidental contact, immediately flush the affected area with clean water and seek medical help.
Please note that the use and handling of chemicals should follow correct safety practices and refer to the relevant laboratory safety manual or consult a professional.
This compound is often used as an intermediate in organic synthesis to construct compounds with specific biological activities. It can also be used for research and development in the field of pesticides and pharmaceuticals.
The preparation is usually prepared by reacting 2,5-difluoro-N-picoline with ammonium bromide. The specific preparation method is as follows:
1. Dissolve 2,5-difluoro-N-picoline in an appropriate amount of solvent.
2. Ammonium bromide was added to the above solution.
3. Stir the reaction at an appropriate temperature for a period of time.
4. Filter the product and dry it to get it.
Regarding safety, it should be handled with caution. It may irritate the eyes, skin and respiratory system. During use, appropriate personal protective equipment should be worn to avoid direct contact. At the same time, it should be operated in a well-ventilated place to avoid inhaling its vapor or dust. In case of accidental contact, immediately flush the affected area with clean water and seek medical help.
Please note that the use and handling of chemicals should follow correct safety practices and refer to the relevant laboratory safety manual or consult a professional.
Last Update：2024-04-09 21:54:55
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View History
2-Bromo-5-Fluoro-3-Picoline
Tris(2-cyanoethyl)phosphine
L-2-氨基-3-苯基丙酸
聚肌苷酸-聚胞苷酸
6-氯吲哚-2-羧酸乙酯
ETHYL 1-BOC-3-PYRROLIDINECARBOXYLATE
2,5-DIBROMO-3-OCTYLTHIOPHENE
双(环戊二烯)氢氯锆
6-甲基-2-羟基吡啶
Tris(2-cyanoethyl)phosphine
L-2-氨基-3-苯基丙酸
聚肌苷酸-聚胞苷酸
6-氯吲哚-2-羧酸乙酯
ETHYL 1-BOC-3-PYRROLIDINECARBOXYLATE
2,5-DIBROMO-3-OCTYLTHIOPHENE
双(环戊二烯)氢氯锆
6-甲基-2-羟基吡啶