2-(Trifluoromethyl)pyridine-5-carboxaldehyde

2-(Trifluoromethyl)pyridine-5-carboxaldehyde - Names and Identifiers

Name	6-(trifluoromethyl)pyridine-3-carboxaldehyde
Synonyms	6-Trifluoromethylnicotinaldehyde 6-(TRIFLUOROMETHYL)NICOTINALDEHYDE 6-(Trifluoromethyl)nicotinaldehyde 5-Formyl-2-(trifluoromethyl)pyridine 6-(trifluoromethyl)pyridine-3-carbaldehyde 6-(Trifuoromethyl)pyridine-3-carboxadehyde 6-(trifluoromethyl)pyridine-3-carboxaldehyde 6-(TRIFLUOROMETHYL)PYRIDINE-3-CARBOXALDEHYDE 2-(Trifluoromethyl)pyridine-5-carboxaldehyde 6-(TrifluoroMethyl)-3-pyridinecarboxaldehyde 6-(TRIFLUOROMETHYL)PYRIDINE-3-CARBOXALDEHYDE, 6-TRIFLUOROMETHYL-PYRIDINE-3-CARBALDEHYDE
CAS	386704-12-7
EINECS	627-410-8
InChI	InChI=1/C7H4F3NO/c8-7(9,10)6-2-1-5(4-12)3-11-6/h1-4H

2-(Trifluoromethyl)pyridine-5-carboxaldehyde - Physico-chemical Properties

Molecular Formula	C7H4F3NO
Molar Mass	175.11
Density	1.369±0.06 g/cm3(Predicted)
Melting Point	52-56 °C
Boling Point	72 °C
Flash Point	93°C
Vapor Presure	0.252mmHg at 25°C
Appearance	Solid
pKa	-1.25±0.22(Predicted)
Storage Condition	2-8°C
Sensitive	Air Sensitive
Refractive Index	1.476
MDL	MFCD01862647
Physical and Chemical Properties	Melting point 53°C boiling point 72°C flash point 93°C

2-(Trifluoromethyl)pyridine-5-carboxaldehyde - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R43 - May cause sensitization by skin contact R25 - Toxic if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36/37 - Wear suitable protective clothing and gloves. S28 - After contact with skin, wash immediately with plenty of soap-suds.
UN IDs	UN 2811 6.1/PG 3
WGK Germany	3
Hazard Note	Irritant
Hazard Class	6.1
Packing Group	Ⅲ

2-(Trifluoromethyl)pyridine-5-carboxaldehyde - Introduction

6-(trifluoromethyl)pyridine-3-carboxaldehyde is an organic compound with the chemical formula C7H4F3NO. It has a colorless to light yellow liquid with a special benzene ring and pyridine ring structure.

6-(trifluoromethyl)pyridine-3-carboxaldehyde is commonly used as an intermediate in organic synthesis and is widely used in the synthesis of drugs and pesticides. It can be used to synthesize compounds containing trifluoromethyl groups, which generally have good biological activity and antioxidant capacity.

The method for preparing 6-(trifluoromethyl)pyridine-3-carboxaldehyde is mainly to prepare 3-aminopyridine from pyridine, and then react it with trifluoromethyl anhydride to generate 6-(trifluoromethyl)pyridin -3-amine, which is then oxidized to the corresponding aldehyde.

When using safely, it should be noted that the compound is irritating and corrosive, and avoid contact with skin and eyes. Wear appropriate protective equipment such as gloves and goggles during operation. In addition, it should be operated in a well-ventilated place to avoid inhaling its vapors. It is best to store it in a sealed container, away from fire and oxidizing agents.

Last Update：2024-04-09 21:32:40