2,6-DI(TRIFLUOROMETHYL)QUINOLIN-4-OL
2,6-Bis(trifluoromethyl)-4-hydroxyquinoline
CAS: 35877-04-4
Molecular Formula: C11H5F6NO
2,6-DI(TRIFLUOROMETHYL)QUINOLIN-4-OL - Names and Identifiers
2,6-DI(TRIFLUOROMETHYL)QUINOLIN-4-OL - Physico-chemical Properties
| Molecular Formula | C11H5F6NO |
| Molar Mass | 281.15 |
| Density | 1.542±0.06 g/cm3(Predicted) |
| Melting Point | 280-290°C |
| Boling Point | 305.9±37.0 °C(Predicted) |
| Flash Point | 87°C |
| Vapor Presure | 0.115mmHg at 25°C |
| pKa | 5.84±0.40(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.467 |
2,6-DI(TRIFLUOROMETHYL)QUINOLIN-4-OL - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection |
| HS Code | 29334900 |
| Hazard Class | IRRITANT |
2,6-DI(TRIFLUOROMETHYL)QUINOLIN-4-OL - Introduction
2,6-Bis(trifluoromethyl)-4-hydroxyquinoline is an organic compound with the chemical structure of C11H4F6NOH. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 2,6-Bis(trifluoromethyl)-4-hydroxyquinoline is a white to light yellow solid.
-Solubility: Soluble in organic solvents such as acetone and dichloromethane, slightly soluble in ethanol and ether.
-Melting point: The melting point of this compound is about 185-189°C.
-Stability: Stable at room temperature, but avoid contact with strong oxidants and strong acids.
Use:
- 2,6-Bis(trifluoromethyl)-4-hydroxyquinoline is commonly used as a reagent in organic synthesis and can be used for the substitution reaction of aromatic hydrocarbons.
-It can also be used as a raw material for the synthesis of fluorescent dyes, photosensitizers and pharmaceutical intermediates.
Preparation Method: The synthesis of
- 2,6-Bis(trifluoromethyl)-4-hydroxyquinoline is generally obtained by the oxidation reaction of benzo [d] isoindoline.
-The specific preparation method can be used to generate 2,6-bis (trifluoromethyl)-4-nitroquinoline by the addition reaction of chloronitrobenzene and trifluoromethyl, and then obtain the target product by reduction reaction.
Safety Information:
- 2,6-Bis(trifluoromethyl)-4-hydroxyquinoline is considered to be less toxic under normal operating conditions.
-However, as a chemical substance, it still needs to be operated under suitable laboratory conditions, avoid contact with skin and eyes, and avoid inhalation.
-Care should be taken to use personal protective equipment, such as lab gloves, safety glasses and protective clothing.
-When waste is disposed of, it should be disposed of in accordance with local regulations.
Nature:
-Appearance: 2,6-Bis(trifluoromethyl)-4-hydroxyquinoline is a white to light yellow solid.
-Solubility: Soluble in organic solvents such as acetone and dichloromethane, slightly soluble in ethanol and ether.
-Melting point: The melting point of this compound is about 185-189°C.
-Stability: Stable at room temperature, but avoid contact with strong oxidants and strong acids.
Use:
- 2,6-Bis(trifluoromethyl)-4-hydroxyquinoline is commonly used as a reagent in organic synthesis and can be used for the substitution reaction of aromatic hydrocarbons.
-It can also be used as a raw material for the synthesis of fluorescent dyes, photosensitizers and pharmaceutical intermediates.
Preparation Method: The synthesis of
- 2,6-Bis(trifluoromethyl)-4-hydroxyquinoline is generally obtained by the oxidation reaction of benzo [d] isoindoline.
-The specific preparation method can be used to generate 2,6-bis (trifluoromethyl)-4-nitroquinoline by the addition reaction of chloronitrobenzene and trifluoromethyl, and then obtain the target product by reduction reaction.
Safety Information:
- 2,6-Bis(trifluoromethyl)-4-hydroxyquinoline is considered to be less toxic under normal operating conditions.
-However, as a chemical substance, it still needs to be operated under suitable laboratory conditions, avoid contact with skin and eyes, and avoid inhalation.
-Care should be taken to use personal protective equipment, such as lab gloves, safety glasses and protective clothing.
-When waste is disposed of, it should be disposed of in accordance with local regulations.
Last Update：2024-04-09 20:45:29
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Product Name: 2,6-Bis(trifluoromethyl)quinolin-4-ol Request for quotationCAS: 35877-04-4
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CAS: 35877-04-4
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CAS: 35877-04-4
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View History
2,6-DI(TRIFLUOROMETHYL)QUINOLIN-4-OL
1,2-双(二五氟代苯基磷基)-乙烷
Benzene, 5-bromo-1-fluoro-2-methyl-3-nitro-
4-(三氟甲基)-1,2-二氯苯
N-(7H-Purin-6-yl)hydroxylamine
2-[(4-amino-2-nitrophenyl)amino]ethanol
4-methylbenzothiazol-2(3H)-one hydrazone
1,2-Benzenediol, 3-bromo-
1,2-双(二五氟代苯基磷基)-乙烷
Benzene, 5-bromo-1-fluoro-2-methyl-3-nitro-
4-(三氟甲基)-1,2-二氯苯
N-(7H-Purin-6-yl)hydroxylamine
2-[(4-amino-2-nitrophenyl)amino]ethanol
4-methylbenzothiazol-2(3H)-one hydrazone
1,2-Benzenediol, 3-bromo-