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2,3-Dichlorophenylacetonitrile

2,3-Dichlorophenylacetonitrile

CAS: 3218-45-9

Molecular Formula: C8H5Cl2N

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2,3-Dichlorophenylacetonitrile - Names and Identifiers

Name 2,3-Dichlorophenylacetonitrile
Synonyms 2,3-DICHLOROBENZYL CYANIDE
2,3-Dichlorobenzyl cyanide
2,3-DICHLOROPHENYLACETONITRILE
2,3-Dichlorophenylacetonitrile
2,3-Dichlorobenzene acetonitrile
2-(2,3-Dichlorophenyl)acetonitrile
Benzeneacetonitrile, 2,3-dichloro-
CAS 3218-45-9
InChI InChI=1/C8H5Cl2N/c9-7-3-1-2-6(4-5-11)8(7)10/h1-3H,4H2

2,3-Dichlorophenylacetonitrile - Physico-chemical Properties

Molecular FormulaC8H5Cl2N
Molar Mass186.04
Density1.333±0.06 g/cm3(Predicted)
Melting Point66-69 °C
Boling Point115°C 1mm
Flash Point125.9°C
Vapor Presure0.00218mmHg at 25°C
Storage ConditionSealed in dry,Room Temperature
Refractive Index1.565

2,3-Dichlorophenylacetonitrile - Risk and Safety

Hazard SymbolsXn - Harmful
Harmful
Risk CodesR36/37/38 - Irritating to eyes, respiratory system and skin.
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
Safety DescriptionS36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S22 - Do not breathe dust.
UN IDs3439
Hazard Class6.1
Packing GroupIII

2,3-Dichlorophenylacetonitrile - Introduction

2, is an organic compound with the chemical formula C8H5Cl2N. It is a colorless or light yellow liquid with a pungent odor.

2, The main use of the salt is as a starting material or intermediate in organic synthesis. It can be used to synthesize other compounds, such as pesticides, drugs and dyes. Due to its cyano group, it can undergo further functional group transfer reactions by reaction with electrophiles. In organic synthesis, it is often used in the synthesis of heterocyclic compounds and indole derivatives.

The method of preparing 2 is generally obtained from p-xylene through chlorination and cyanidation. There are various specific preparation methods, for example, p-xylene can be reacted with hydrogen cyanide to obtain 2,3-dichlorophenylacetic acid, which is then decarboxylated to obtain the target product.

When using and storing 2, you need to pay attention to its toxicity and irritation. It is irritating to the skin, eyes and respiratory tract and may cause inflammation and allergic reactions. Wear protective gloves, goggles and breathing apparatus during operation, and provide good ventilation. At the same time, it should be stored away from fire and oxidizing agents.
Last Update:2024-04-09 21:11:58
2,3-Dichlorophenylacetonitrile
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View History
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