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1H-Indazole-7-carboxylicacid

1H-Indazole-7-carboxylicacid

CAS: 677304-69-7

Molecular Formula: C8H6N2O2

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1H-Indazole-7-carboxylicacid - Names and Identifiers

Name 1H-Indazole-7-carboxylicacid
Synonyms 7-Carboxy-1H-indazole
Niraparib Intermediate4
7-INDAZOLE CARBOXYLIC ACID
7-INDAZOLE CARBOXYLLIC ACID
1H-Indazol-7-carboxylic acid
1H-Indazole-7-carboxylicacid
1H-indazole-7-carboxylic acid
1H-INDAZOLE-7-CARBOXYLIC ACID
1H-Indazole-7-Carboxylic Acid
7-(1H)Indazole carboxylic acid
CAS 677304-69-7

1H-Indazole-7-carboxylicacid - Physico-chemical Properties

Molecular FormulaC8H6N2O2
Molar Mass162.15
Density1.506±0.06 g/cm3(Predicted)
Melting Pointca 240℃
Boling Point443.7±18.0 °C(Predicted)
Solubility DMSO (Slightly), Methanol (Slightly)
AppearanceCrystalline powder
ColorWhite to yellow
pKa3.71±0.10(Predicted)
Storage ConditionSealed in dry,Room Temperature
MDLMFCD06804572

1H-Indazole-7-carboxylicacid - Risk and Safety

HS Code29339980

1H-Indazole-7-carboxylicacid - Introduction

It is an organic compound with the chemical formula C9H6N2O2. It is a compound similar to indazole in structure, in which a carboxyl group (-COOH) is substituted in position 1.

Regarding its nature, it is a white to yellow crystal with low solubility. It decomposes below its melting point. This compound is stable in air, but may undergo combustion reactions when exposed to high temperatures or strong oxidants.

In the field of medicine has a wide range of applications. It is an important intermediate for the synthesis of various compounds with biological activity. It is used in the process of drug development to prepare antibacterial drugs, anti-tumor drugs and anti-inflammatory drugs. In addition, it can also be used for the preparation of dyes and rubber auxiliaries.

Regarding the preparation method, a common method for synthesizing phenyl is to react acetophenone with sulfuric acid and nitrous acid to form pyrrole and further oxidative acylation to obtain the compound.

Regarding safety information, due to the specific application and use of the metal may be different, it is necessary to carry out appropriate safety operations and protective measures under specific experimental conditions. When handling and using the compound, it is recommended to wear appropriate personal protective equipment, such as laboratory gloves, glasses, and laboratory outdoor hoods, to avoid contact, inhalation, or ingestion. At the same time, it should be stored in a cool and dry place, away from fire and flammable materials. In case of leakage or accident, appropriate treatment and disposal measures shall be taken in time.
Last Update:2024-04-09 21:54:55
1H-Indazole-7-carboxylicacid
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1H-Indazole-7-carboxylicacid
4,4-azo-3-hydroxynaphthalene-1-sulfonate
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