19847-10-0
2-Pyrazinecarbonyl chloride
CAS: 19847-10-0
Molecular Formula: C5H3ClN2O
19847-10-0 - Names and Identifiers
| Name | 2-Pyrazinecarbonyl chloride |
| Synonyms | TIMTEC-BB SBB010290 ASINEX-REAG BAS 07703829 pyrazinecarbonyl chloride Pyrazinecarbonyl chloride 2-Pyrazinecarbonyl chloride 2-PYRAZINECARBONYL CHLORIDE Pyrazine-2-carbonyl chloride PYRAZINE-2-CARBONYL CHLORIDE PYRAZINE-2-CARBOXYLIC ACID CHLORIDE |
| CAS | 19847-10-0 |
| EINECS | 243-367-4 |
| InChI | InChI=1/C5H3ClN2O/c6-5(9)4-3-7-1-2-8-4/h1-3H |
19847-10-0 - Physico-chemical Properties
| Molecular Formula | C5H3ClN2O |
| Molar Mass | 142.54 |
| Density | 1.393±0.06 g/cm3(Predicted) |
| Melting Point | 41°C |
| Boling Point | 214.5±20.0 °C(Predicted) |
| Flash Point | 83.5°C |
| Water Solubility | Reacts with water. |
| Vapor Presure | 0.155mmHg at 25°C |
| pKa | -2.50±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | Moisture Sensitive |
| Refractive Index | 1.551 |
| MDL | MFCD00792886 |
19847-10-0 - Risk and Safety
| Hazard Symbols | C - Corrosive |
| Risk Codes | 34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | 3265 |
| Hazard Class | 8 |
| Packing Group | II |
19847-10-0 - Introduction
2-Pyrazinecarbonyl chloride, also known as the formula ClCOCHC(NH2) = NC5H4, is an organic compound. The following is a description of the nature, use, formulation and safety information of 2-Pyrazinecarbonyl chloride:
Nature:
-Appearance: colorless liquid
-Molecular formula: C6H4ClNO
-Molecular weight: 141.56g/mol
-Boiling point: 260-261 ° C
-Density: 1.318g/cm³
Use:
2-Pyrazinecarbonyl chloride is mainly used in organic synthesis reactions and is commonly used as acylation reagent, substitution reagent and reaction intermediate. It has a wide range of applications in the construction of nitrogen heterocyclic compounds, such as the synthesis of mold penicillin antibiotics, Pyrazine compounds and other drugs and pesticides.
Method:
The preparation of 2-Pyrazinecarbonyl chloride is mainly obtained by reacting pyrazin-2-amine with acid chloride. The specific preparation method is as follows:
1. First, the pyrazin-2-amine is added to the organic solvent in which the acid chloride is dissolved.
2. Slowly add pyrazin-2-amine Dropwise and keep the temperature of the reaction system at -10 to 0°C.
3. After completion of the reaction, the reaction solution was washed with water and dried.
4. Finally, the 2-Pyrazinecarbonyl chloride product was obtained by distillation purification.
Safety Information:
2-Pyrazinecarbonyl chloride is an organic compound. The following safety precautions should be paid attention to when using it:
-The compound is irritating and corrosive, avoid contact with skin and eyes.
-Wear appropriate personal protective equipment during operation, including protective goggles, lab gloves and protective clothing.
-Maintain good ventilation during operation.
-Avoid storing or handling this compound with flammable substances as it can cause a fire or explosion.
-When using or storing, pay attention to comply with local laws and regulations.
Before using 2-Pyrazinecarbonyl chloride, please be sure to read the relevant safety information and operating instructions carefully, and take appropriate safety measures according to the specific situation.
Nature:
-Appearance: colorless liquid
-Molecular formula: C6H4ClNO
-Molecular weight: 141.56g/mol
-Boiling point: 260-261 ° C
-Density: 1.318g/cm³
Use:
2-Pyrazinecarbonyl chloride is mainly used in organic synthesis reactions and is commonly used as acylation reagent, substitution reagent and reaction intermediate. It has a wide range of applications in the construction of nitrogen heterocyclic compounds, such as the synthesis of mold penicillin antibiotics, Pyrazine compounds and other drugs and pesticides.
Method:
The preparation of 2-Pyrazinecarbonyl chloride is mainly obtained by reacting pyrazin-2-amine with acid chloride. The specific preparation method is as follows:
1. First, the pyrazin-2-amine is added to the organic solvent in which the acid chloride is dissolved.
2. Slowly add pyrazin-2-amine Dropwise and keep the temperature of the reaction system at -10 to 0°C.
3. After completion of the reaction, the reaction solution was washed with water and dried.
4. Finally, the 2-Pyrazinecarbonyl chloride product was obtained by distillation purification.
Safety Information:
2-Pyrazinecarbonyl chloride is an organic compound. The following safety precautions should be paid attention to when using it:
-The compound is irritating and corrosive, avoid contact with skin and eyes.
-Wear appropriate personal protective equipment during operation, including protective goggles, lab gloves and protective clothing.
-Maintain good ventilation during operation.
-Avoid storing or handling this compound with flammable substances as it can cause a fire or explosion.
-When using or storing, pay attention to comply with local laws and regulations.
Before using 2-Pyrazinecarbonyl chloride, please be sure to read the relevant safety information and operating instructions carefully, and take appropriate safety measures according to the specific situation.
Last Update：2024-04-09 21:01:54
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Tel: 400-968-2212
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Mobile: 18916960931
QQ: 3623107365
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Spot supply
Product Name: Pyrazine-2-carbonyl chloride Visit Supplier Webpage Request for quotationCAS: 19847-10-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: Pyrazine-2-Carbonyl Chloride Visit Supplier Webpage Request for quotation
CAS: 19847-10-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 19847-10-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
19847-10-0
914087-74-4
乙酸茴香酯
二磷酸四氢钙
甲烷同位素气体
59572-10-0
邻异丙基苯酚
四水合二碘化铁
thiosulfuric acid (h2s2o3), disodium salt
760961-03-3
914087-74-4
乙酸茴香酯
二磷酸四氢钙
甲烷同位素气体
59572-10-0
邻异丙基苯酚
四水合二碘化铁
thiosulfuric acid (h2s2o3), disodium salt
760961-03-3