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19501-58-7

4-Methoxyphenylhydrazine hydrochloride

CAS: 19501-58-7;70672-74-1

Molecular Formula: C7H11ClN2O

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19501-58-7 - Names and Identifiers

Name 4-Methoxyphenylhydrazine hydrochloride
Synonyms (4-methoxyphenyl)hydrazine
4-Methoxyphenyhydrozine HCL
p-anisidinoammonium chloride
4-Anisylhydrazine Hydrochloride
4-Hydrozinobenzeno Sulfonamide HCL
4-Methoxyphenylhydrazine hydrochloride
4-METHOXYPHENYLHYDRAZINIUM CHLORIDE FOR
4-methoxy phenyl hydrazine hydrochloride
[(4-methoxyphenyl)amino]azanium chloride
[(4-methoxyphenyl)amino]ammonium chloride
(4-methoxyphenyl)hydrazine dihydrochloride
4-Methoxyphenylhydrazinium chloride for synthesis
IndoMethacin iMpurity (4-Methoxyphenylhydrazine hydrochloride)
CAS 19501-58-7
70672-74-1
EINECS 243-115-3
InChI InChI=1/C7H10N2O.ClH/c1-10-7-5-3-2-4-6(7)9-8;/h2-5,9H,8H2,1H3;1H

19501-58-7 - Physico-chemical Properties

Molecular FormulaC7H11ClN2O
Molar Mass174.63
Melting Point160-162°C (dec.)(lit.)
Boling Point263.5°C at 760 mmHg
Flash Point113.2°C
Water Solubilitysoluble
Vapor Presure0.0103mmHg at 25°C
AppearanceGrey yellow pink solid
ColorSlightly pink to gray to purple
BRN3566583
Storage ConditionKeep Cold
MDLMFCD00012945
Physical and Chemical PropertiesMelting point 160-162°C (dec.)
water-soluble soluble
UseApplied to dyes and pharmaceutical intermediates.

19501-58-7 - Risk and Safety

Risk CodesR20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety DescriptionS36/37 - Wear suitable protective clothing and gloves.
S36 - Wear suitable protective clothing.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
UN IDs2811
WGK Germany3
HS Code29280090
Hazard NoteIrritant/Harmful
Hazard ClassIRRITANT, KEEP COLD
Packing GroupIII

19501-58-7 - Reference Information

Use 4-methoxyphenylhydrazine hydrochloride is an intermediate, mainly used to produce phenylhydrazine compounds, and can also be used to produce other chemical products, such as 4-nitroindole and apixaban.
Applied to dyes and pharmaceutical intermediates
Preparation 4-methoxyphenylhydrazine hydrochloride can be prepared from aniline through diazotization reaction.
Take aniline, hydrochloric acid and sodium nitrite, the molar ratio between them is 1: 3.2: 1.0, first add hydrochloric acid, then add ammonium nitrite at 5 ℃, and react at 0~20 ℃ for 40 minutes to generate chlorinated diazobenzene; According to the molar ratio of aniline to 1: 3.5: 2.5, ammonium sulfite and hydrochloric acid are added, and reduction, hydrolysis and acidification are carried out in the reduction kettle, the reduction time is 60~70 minutes, and the hydrolysis and acidification time is 50 minutes. First, ammonium sulfite reacts with excess hydrochloric acid to produce ammonium bisulfite, ammonium bisulfite, ammonium sulfite reacts with chlorinated diazobenzene to form phenylhydrazine disulfonate, and then reacts with hydrochloric acid for hydrolysis and acid analysis The reaction, and after spin-drying, 4-methoxyphenylhydrazine hydrochloride is prepared.
Last Update:2024-04-09 21:01:54
19501-58-7
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Email: wuhao@highfine.com
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