19314-10-4
3-Chloro-N-(4-Hydroxyphenyl)Propionamide
CAS: 19314-10-4
Molecular Formula: C9H10ClNO2
19314-10-4 - Names and Identifiers
| Name | 3-Chloro-N-(4-Hydroxyphenyl)Propionamide |
| Synonyms | 3-chloro-N-(4-hydroxyphenyl)propanamide 3-CHLORO-N-(4-HYDROXYPHENYL)PROPIONAMIDE 3-Chloro-N-(4-Hydroxyphenyl)Propionamide propanamide, 3-chloro-N-(4-hydroxyphenyl)- Propanamide, 3-chloro-N-(4-hydroxyphenyl)- |
| CAS | 19314-10-4 |
| InChI | InChI=1/C9H10ClNO2/c10-6-5-9(13)11-7-1-3-8(12)4-2-7/h1-4,12H,5-6H2,(H,11,13) |
19314-10-4 - Physico-chemical Properties
| Molecular Formula | C9H10ClNO2 |
| Molar Mass | 199.63 |
| Density | 1.341g/cm3 |
| Boling Point | 433.8°C at 760 mmHg |
| Flash Point | 216.2°C |
| Vapor Presure | 3.92E-08mmHg at 25°C |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.614 |
19314-10-4 - Introduction
3-choro-n-(4-Hydroxyphenyl)Propionamide, with the chemical formula C9H9ClNO2, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 3-Chloro-N-(4-Hydroxyphenyl)Propionamide is a white crystalline solid.
-Solubility: It is soluble in organic solvents such as alcohols, esters and ethers, and slightly soluble in water.
-Melting point: Its melting point range is 150-155 degrees Celsius.
Use:
-Pharmaceutical field: 3-choro-n-(4-Hydroxyphenyl)Propionamide is a Propionamide compound with certain pharmaceutical activity. It is used in the synthesis of certain drugs, such as non-steroidal anti-inflammatory drugs.
-Cosmetics field: It is also used as a raw material in cosmetics for skin moisturizing and antioxidant effects.
Method:
3-choro-n-(4-Hydroxyphenyl)Propionamide can be prepared by the following steps:
1. 4-hydroxybenzoic acid was obtained by reacting 4-hydroxybenzaldehyde with chloroacetic acid.
2.4-Hydroxybenzoic acid is reacted with chloro sulfite to obtain 4-Hydroxybenzoic acid thionyl chloride.
3. 4-hydroxybenzoic acid thionyl chloride is reacted with N,N-dimethylethylenediamine to give 3-chloro-N-(4-Hydroxyphenyl)Propionamide.
Safety Information:
- 3-Chloro-N-(4-Hydroxyphenyl)Propionamide should avoid direct contact with skin and eyes to avoid irritation or allergy. Personal protective equipment such as gloves and goggles should be used during use.
-Observe relevant safety procedures during storage and handling.
-When swallowing or inadvertent contact occurs, rinse immediately with plenty of water and seek medical help.
Nature:
-Appearance: 3-Chloro-N-(4-Hydroxyphenyl)Propionamide is a white crystalline solid.
-Solubility: It is soluble in organic solvents such as alcohols, esters and ethers, and slightly soluble in water.
-Melting point: Its melting point range is 150-155 degrees Celsius.
Use:
-Pharmaceutical field: 3-choro-n-(4-Hydroxyphenyl)Propionamide is a Propionamide compound with certain pharmaceutical activity. It is used in the synthesis of certain drugs, such as non-steroidal anti-inflammatory drugs.
-Cosmetics field: It is also used as a raw material in cosmetics for skin moisturizing and antioxidant effects.
Method:
3-choro-n-(4-Hydroxyphenyl)Propionamide can be prepared by the following steps:
1. 4-hydroxybenzoic acid was obtained by reacting 4-hydroxybenzaldehyde with chloroacetic acid.
2.4-Hydroxybenzoic acid is reacted with chloro sulfite to obtain 4-Hydroxybenzoic acid thionyl chloride.
3. 4-hydroxybenzoic acid thionyl chloride is reacted with N,N-dimethylethylenediamine to give 3-chloro-N-(4-Hydroxyphenyl)Propionamide.
Safety Information:
- 3-Chloro-N-(4-Hydroxyphenyl)Propionamide should avoid direct contact with skin and eyes to avoid irritation or allergy. Personal protective equipment such as gloves and goggles should be used during use.
-Observe relevant safety procedures during storage and handling.
-When swallowing or inadvertent contact occurs, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-09 15:17:54
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Product Name: 3-CHLORO-N-(4-HYDROXYPHENYL)PROPIONAMIDE Visit Supplier Webpage Request for quotation
CAS: 19314-10-4
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View History
19314-10-4
O-Methyl Phosphorodichloridit
p-Methoxybenzaldazine
664374-03-2
1894189-67-3
trimethyl-aceticaci
1396969-20-2
Ethoxylated Bisphenol A
210169-57-6
C.I. Acid Red 111, disodium salt
O-Methyl Phosphorodichloridit
p-Methoxybenzaldazine
664374-03-2
1894189-67-3
trimethyl-aceticaci
1396969-20-2
Ethoxylated Bisphenol A
210169-57-6
C.I. Acid Red 111, disodium salt