188011-69-0
4-[(5-bromopyridin-2-yl)amino]-4-oxobutanoic acid
CAS: 188011-69-0
Molecular Formula: C9H9BrN2O3
188011-69-0 - Names and Identifiers
188011-69-0 - Physico-chemical Properties
| Molecular Formula | C9H9BrN2O3 |
| Molar Mass | 273.08 |
| Density | 1.711 |
| Melting Point | 144°C(lit.) |
| Solubility | DMSO: ≥5mg/mL |
| Appearance | White solid |
| Color | white to tan |
| Storage Condition | 2-8°C |
| MDL | MFCD00116442 |
| In vitro study | Bikinin directly targets BIN2 of Arabidopsis GSK-3s and activates brassinosteroid-dependent gene expression. Bikinin also inhibits RD26 expression, and inhibits the induction of GUS activity by 150 mM NaCl in the RD26pro:GUS line. |
| In vivo study | Bikinin strongly inhibits abscisic acid signaling outputs, and inhibits T180 phosphorylation of SnRK2.3 and its kinase activity in vivo. |
188011-69-0 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R36 - Irritating to the eyes |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
188011-69-0 - Reference
| Reference Show more | 1. [IF=5.923] Jingjue Zeng et al."Functional Characterization of VvSK Gene Family in Grapevine Revealing Their Role in Berry Ripening."Int J Mol Sci. 2020 Jan;21(12):4336 |
188011-69-0 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.662 ml | 18.309 ml | 36.618 ml |
| 5 mM | 0.732 ml | 3.662 ml | 7.324 ml |
| 10 mM | 0.366 ml | 1.831 ml | 3.662 ml |
| 5 mM | 0.073 ml | 0.366 ml | 0.732 ml |
Last Update：2024-01-02 23:10:35
188011-69-0 - Reference Information
| biological activity | Bikinin is an ATP competitive Arabidopsis GSK-3 inhibitor, which acts as a potent activator of brassinosteroid (BR) signal. |
| in vitro study | Bikinin directly targets BIN2 of Arabidopsis GSK-3s and activates brassinosteroid-dependent gene expression. Bikinin also inhibits RD26 expression, and inhibits the induction of GUS activity by 150 mM NaCl in the RD26pro:GUS line. |
| in vivo study | Bikinin strongly inhibits abscisic acid signaling outputs, and inhibits T180 phosphorylation of SnRK2.3 and its kinase activity in vivo. |
| target | GSK-3 |
Last Update：2024-04-09 21:54:55
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View History
188011-69-0
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