1823989-97-4
2-(4-bromo-3-fluorophenyl)-2,2-difluoroethan-1-ol
CAS: 1823989-97-4
Molecular Formula: C8H6BrF3O
1823989-97-4 - Names and Identifiers
| Name | 2-(4-bromo-3-fluorophenyl)-2,2-difluoroethan-1-ol |
| Synonyms | Benzeneethanol, 4-bromo-β,β,3-trifluoro- 2-(4-bromo-3-fluorophenyl)-2,2-difluoroethan-1-ol |
| CAS | 1823989-97-4 |
1823989-97-4 - Physico-chemical Properties
| Molecular Formula | C8H6BrF3O |
| Molar Mass | 255.03 |
| Density | 1.678±0.06 g/cm3(Predicted) |
| Boling Point | 299.2±35.0 °C(Predicted) |
| pKa | 13.21±0.10(Predicted) |
1823989-97-4 - Introduction
2-(4-bromo-3-fluorophenyl)-2,2-difluoroethan-1-ol is an organic compound. Its molecular formula is C8H6BrF2O and its molecular weight is 235.03g/mol. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: colorless liquid
-Melting point:-28 ° C
-Boiling point: 178 ° C
-Density: 1.6g/cm³
-Solubility: Soluble in organic solvents such as ethanol and dimethylformamide
Use:
- 2-(4-bromo-3-fluorophenyl)-2,2-difluoroethan-1-ol is a commonly used raw material in organic synthesis. It can be used as a catalyst, reagent or intermediate for the synthesis of other compounds.
-The compound also has certain applications in drug development and pesticide manufacturing.
Method:
2-(4-bromo-3-fluorophenyl)-2,2-difluoroethan-1-ol can be synthesized by the following steps:
1. First, 4-bromo-3-fluorophenylacetic acid is reacted with sodium hydroxide to produce 2-(4-bromo-3-fluorophenyl) acetic acid.
2. Then, 2-(4-bromo-3-fluorophenyl) acetic acid and 2,2-difluoroacetic anhydride are reacted to produce 2-(4-bromo-3-fluorophenyl)-2,2-Difluoroacetic acid.
3. Finally, 2-(4-bromo-3-fluorophenyl)-2,2-difluoroacetic acid is reduced to give 2-(4-bromo-3-fluorophenyl)-2,2-difluoroethan-1-ol.
Safety Information:
- 2-(4-bromo-3-fluorophenyl)-2,2-difluoroethan-1-ol is an organic compound and has certain toxicity, so it is necessary to take appropriate safety precautions during operation, such as wearing gloves and glasses.
-Avoid breathing its vapor or dust, and maintain a well-ventilated operating environment.
-Avoid contact with skin or eyes. In case of contact, rinse immediately with plenty of water and seek medical help.
-The compound should be stored in a sealed container, away from heat and fire sources.
Nature:
-Appearance: colorless liquid
-Melting point:-28 ° C
-Boiling point: 178 ° C
-Density: 1.6g/cm³
-Solubility: Soluble in organic solvents such as ethanol and dimethylformamide
Use:
- 2-(4-bromo-3-fluorophenyl)-2,2-difluoroethan-1-ol is a commonly used raw material in organic synthesis. It can be used as a catalyst, reagent or intermediate for the synthesis of other compounds.
-The compound also has certain applications in drug development and pesticide manufacturing.
Method:
2-(4-bromo-3-fluorophenyl)-2,2-difluoroethan-1-ol can be synthesized by the following steps:
1. First, 4-bromo-3-fluorophenylacetic acid is reacted with sodium hydroxide to produce 2-(4-bromo-3-fluorophenyl) acetic acid.
2. Then, 2-(4-bromo-3-fluorophenyl) acetic acid and 2,2-difluoroacetic anhydride are reacted to produce 2-(4-bromo-3-fluorophenyl)-2,2-Difluoroacetic acid.
3. Finally, 2-(4-bromo-3-fluorophenyl)-2,2-difluoroacetic acid is reduced to give 2-(4-bromo-3-fluorophenyl)-2,2-difluoroethan-1-ol.
Safety Information:
- 2-(4-bromo-3-fluorophenyl)-2,2-difluoroethan-1-ol is an organic compound and has certain toxicity, so it is necessary to take appropriate safety precautions during operation, such as wearing gloves and glasses.
-Avoid breathing its vapor or dust, and maintain a well-ventilated operating environment.
-Avoid contact with skin or eyes. In case of contact, rinse immediately with plenty of water and seek medical help.
-The compound should be stored in a sealed container, away from heat and fire sources.
Last Update：2024-04-09 21:01:54
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Product Name: 2-(4-bromo-3-fluorophenyl)-2,2-difluoroethan-1-ol Request for quotationCAS: 1823989-97-4
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 2-(4-bromo-3-fluorophenyl)-2,2-difluoroethan-1-ol Visit Supplier Webpage Request for quotationCAS: 1823989-97-4
Tel: +86-400-900-4166
Email: product@acmec-e.com
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View History
1823989-97-4
1118917-09-1
Phosphoric acid tris(2-ethylhexyl) ester
m-fluoroiodobenzene
380665-15-6
2-溴苯甲酰氯
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1118917-09-1
Phosphoric acid tris(2-ethylhexyl) ester
m-fluoroiodobenzene
380665-15-6
2-溴苯甲酰氯
GAMMA-氧代吲哚-3-丁酸
iodo(methylsulfanyl)methane
3-甲氧基哒嗪
AMBERLITE XAD-16 非离子型大孔树脂