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18063-03-1

2,6-Difluorobenzamide

CAS: 18063-03-1

Molecular Formula: C7H5F2NO

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18063-03-1 - Names and Identifiers

Name 2,6-Difluorobenzamide
Synonyms uorobenzamide
2,6-Difluorbenzamid
2,6-Difluorobenzamide
2,6-Difluorobenzoylamide
Fluorine benzaMide 2, 6-2
2,6-difluorobenzoic acid amide
CAS 18063-03-1
EINECS 241-972-8
InChI InChI=1/C7H5F2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)
InChIKey AVRQBXVUUXHRMY-UHFFFAOYSA-N

18063-03-1 - Physico-chemical Properties

Molecular FormulaC7H5F2NO
Molar Mass157.12
Density1,199g/cm
Melting Point145-148 °C (lit.)
Boling Point51-52C/15Tor
Flash Point67.3°C
Solubility ethanol: soluble5%, clear to turbid, colorless to light yellow
Vapor Presure0.622mmHg at 25°C
AppearanceWhite crystal
ColorOff-White
BRN2047480
pKa14.54±0.50(Predicted)
Storage ConditionSealed in dry,Room Temperature
Refractive Index1,508
MDLMFCD00007972
Physical and Chemical Properties

Appearance: White-like crystals

UseIt can be used as an intermediate for the synthesis of fluorinated benzoylurea pesticides, and can be used as a variety of insecticides and acaricides, such as fluifolide, difenuron, and difenuron. It is also used in medicine; Intermediates in pesticides and intermediates in organic synthesis for the synthesis of fluorobenzenes Acyl urea pesticide intermediates, from which can be prepared by the fluoride, borteuron, difenuron and other insecticidal, acaricide. It is also used in medicine, liquid crystal materials.

18063-03-1 - Risk and Safety

Risk CodesR36/37/38 - Irritating to eyes, respiratory system and skin.
R20 - Harmful by inhalation
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 - Wear suitable gloves and eye/face protection
S36/37 - Wear suitable protective clothing and gloves.
WGK Germany1
RTECSCV4355050
HS Code29242990
Hazard ClassIRRITANT

18063-03-1 - Nature

Open Data Verified Data

white crystals. The melting point was 143-145 °c.

Last Update:2024-01-02 23:10:35

18063-03-1 - Preparation Method

Open Data Verified Data

prepared from 2,6-chlorobenzonitrile by fluorination and hydrolysis.

Last Update:2022-01-01 10:52:40

18063-03-1 - Application

Open Data Verified Data

This product and the role of phenyl chloroisocyanate, can be prepared by fluorine containing carbamate new insecticide v. Uron. This insecticide has a wide insecticidal spectrum, low toxicity to humans and animals, and little harm to natural enemies. It is a relatively good selective insecticide developed in recent years.

Last Update:2025-08-19 16:24:40

18063-03-1 - Safety

Open Data Verified Data

The product is packed with a cardboard drum lined with a plastic bag, with a net weight of 25kg per barrel, or packaged according to user requirements.

Last Update:2022-01-01 10:52:41

18063-03-1 - Reference Information

LogP0.011-0.25 at 25℃
NIST chemical information Information provided by: webbook.nist.gov (external link)
EPA chemical information Information provided by: ofmpub.epa.gov (external link)
Uses 2,6-difluorobenzamide is an important intermediate in the synthesis of benzoylurea insecticides. It is used to synthesize the next intermediate 2,6-difluorobenzoyl isocyanate, and finally obtain pesticide varieties such as flubolluron, deworm urea, fluidinone, and lice urea. You can also use 2, 6-Difluorobenzamide is directly used in the synthesis of pyrethroid and flubolluron.
This product is used as an intermediate for the synthesis of fluorobenzoylurea pesticides. From it, a variety of insecticides and acaricides such as fluoroburon, Dingchonglong, and dewort urea can be prepared. It is also used in medicine and liquid crystal materials. The product is lined with plastic bags in cardboard barrels with a net weight of 25kg.
It is used as an intermediate for the synthesis of fluorobenzoylurea pesticides. It can produce a variety of insecticides and acaricides such as flubolluron, Dingchonglong, and dewort urea. It is also used in medicine
production method obtained by hydrolysis of 2,6-difluorobenzonitrile. The reaction was carried out in 90% sulfuric acid at a hydrolysis temperature of 70°C.
The preparation method is to use sulfuric acid as a catalyst, 2, 6-difluorobenzonitrile and water undergo a nucleophilic addition reaction to generate 2, 6-difluorobenzamide sulfate, neutralize sulfuric acid with alkali, 2, 6-Difluorobenzamide can be free. The reaction equation is shown in the figure: 2, 6-difluorobenzonitrile and 90% sulfuric acid are added into an enamel reaction kettle, stirred and reacted at 65~70 ℃ for 5 hours, then neutralized with NaOH solution to pH = 6, filtered at a temperature below 20 ℃, washed with a small amount of water to remove the adsorbed sodium sulfate, and dried to obtain 2, 6-difluorobenzamide.
Last Update:2024-04-09 20:49:11
18063-03-1
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Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
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Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: 2,6-Difluorobenzamide Request for quotation
CAS: 18063-03-1
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Hubei Rhema Reference Materials Technology Co., Ltd.
Spot supply
Product Name: Lufenuron Impurity Request for quotation
CAS: 18063-03-1
Tel: 0712-8899838
Email: jy6101@rmastandards.com
Mobile: 86-15787876101
QQ: 2518299249 Click to send a QQ message
Wechat: 15787876101
JIANGSU BSECHEM CHEMICAL TECHNOLOGY CO., LTD.
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Product Name: 2,6-Difluorobenzamide Request for quotation
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Tel: +86-17505207175
Email: 3787852685@qq.com
Mobile: +86-17505207175
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Guangzhou Yuanda New Material Co.,Ltd
Multiple Specifications
Product Name: 2,6-Difluorobenzamide Request for quotation
CAS: 18063-03-1
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
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Shanghai Amole Biotechnology Co., Ltd.
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Product Name: 2,6-Difluorobenzamide Request for quotation
CAS: 18063-03-1
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
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SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
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Product Name: 2,6-Difluorobenzamide Visit Supplier Webpage Request for quotation
CAS: 18063-03-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
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SKYRUN INDUSTRIAL CO.,LTD
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Product Name: 26-Difluorobenzamide Visit Supplier Webpage Request for quotation
CAS: 18063-03-1
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
Wechat: chinaskyrun
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: 2,6-Difluorobenzamide Request for quotation
CAS: 18063-03-1
Tel: 0086-551-65418684
Email: sales@tnjchem.com
     info@tnjchem.com
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